Recurring concern

Unreliable prevention and response to adrenal crisis

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First reported 11 Jan 2016•Latest report 13 Aug 2024

Definition

What this concern includes

Includes failures in controls specifically dedicated to preventing or responding to adrenal crisis and steroid insufficiency, including staff recognition and knowledge, prompts or alerts for adrenal insufficiency or long-term steroid use, continuation of replacement steroids, emergency or stress-dose treatment, and escalation when symptoms suggest adrenal crisis.

Not included

  • Excludes generic staff training, communication, prescribing or medication-administration deficiencies unless they directly concern adrenal insufficiency, steroid dependence or adrenal-crisis prevention and response.
  • Excludes routine steroid treatment or monitoring for conditions without an adrenal-insufficiency or adrenal-crisis safety connection.
  • Excludes confirmed adrenal-crisis treatment failures occurring after the condition was reliably recognised and appropriate emergency response was initiated.
  • Excludes unrelated medication omissions, clinical deterioration or emergency-service failures where steroid insufficiency or adrenal crisis is not the material safety concern.
Reports
6

Distinct published reports

Individual concerns
16

A report can raise multiple concerns

Date range
2016–2024

First to latest report issue date

Stated actions
46

Described in published responses

Reports over time

Reports over time

Reports about this concern issued each year.

* 2026 is projected from reports observed to 7 Sep 2026.

Most frequent recipients

Most frequent recipients

Reports about this concern sent to each recipient.

NHS England4
Association of Ambulance Chief Executives2
Worcestershire Acute Hospitals NHS Trust2
Great Western Hospitals NHS Foundation Trust1
National Institute for Health and Care Excellence1
North East Ambulance Service NHS Foundation Trust1
Royal College of General Practitioners1
Society For Endocrinology1
University Hospitals Plymouth NHS Trust1
West Midlands Ambulance Service University NHS Foundation Trust1

Concerns and responses across reports

Only concerns grouped under this recurring concern are included. Select any concern, action or position to view the source wording.

  1. Teesside and Hartlepool

    AI-generated summary

    Margaret HUNTLEY · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Margaret Huntley died on 10 December 2022 after deteriorating with multi-organ failure associated with dehydration, lack of exogenous steroids and Covid-19 infection. The report identifies delays in recognising her need for steroid medication and in prescribing and administering it. Concerns included ambulance staff understanding and triage guidance regarding steroid medication, use of Steroid Emergency Cards, and GP awareness of ambulance-service patient alerts.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Insufficient awareness of Steroid Emergency Cards

    Wider context from the report

    “3. It is unclear as to whether Margaret Huntley had been issued with a Steroid Emergency Card and/or information around use of such a Card. I am concerned that there needs to be improved usage, and awareness, of Steroid Emergency Cards. ”

    Source location

    Margaret HUNTLEY · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Insufficient usage of Steroid Emergency Cards

    Wider context from the report

    “3. It is unclear as to whether Margaret Huntley had been issued with a Steroid Emergency Card and/or information around use of such a Card. I am concerned that there needs to be improved usage, and awareness, of Steroid Emergency Cards. ”

    Source location

    Margaret HUNTLEY · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of Ambulance Service staff understanding of steroid medication importance and required actions

    Wider context from the report

    “1. There is a lack of understanding amongst (non-clinical and clinical) Ambulance Service staff as to the importance of steroid medication and the steps to be taken should a patient (a) report that they are prescribed steroid medication and/or (b) present with symptoms potentially consistent with steroid insufficiency/Addison’s Crisis. ”

    Source location

    Margaret HUNTLEY · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Include an image of the NHS steroid emergency card in JRCALC steroid-dependent patient guidance to raise awareness among ambulance clinicians.

    Verbatim wording from the response

    “Within our JRCALC guidance for steroid-dependent patients, we have an image of the NHS steroid emergency card. We included this particularly to help raise awareness amongst ambulance clinicians. In addition ambulance clinicians can often gain access to the patients’ health care record where clinical information such as steroid dependency may be available.”

    Source location

    Response from Association of Ambulance Chief Executives
    Page 2 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Issue a National Patient Safety Alert introducing the Steroid Emergency Card to support early recognition and treatment of adult adrenal crisis.

    Verbatim wording from the response

    “We note that your concerns are not limited to adrenal insufficiency, but that you have also raised a concern over the awareness and usage of Steroid Emergency Cards. NHS England issued a National Patient Safety Alert in August 2020 regarding the introduction of a new Steroid Emergency Card to support early recognition and treatment of adrenal crisis in adults. The Alert is available here: https://www.england.nhs.uk/publication/national-patient-safety-alert-steroid-emergency-card-to-support-early-recognition-and-treatment-of-adrenal-crisis-in-adults/.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Publish an Addison’s Self Help Group website link and conduct social-media awareness activity about steroid emergency cards.

    Verbatim wording from the response

    “To ensure consistency with existing public messaging we have included a link to the Addisons Self Help Group website on the NEAS website and have undertaken an awareness campaign via our social media platforms.”

    Source location

    Response from NE Ambulance Service
    Page 6 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Review NHS Pathways content and classify callers declaring a Steroid Emergency Card as complex calls requiring clinical input.

    Verbatim wording from the response

    “The Alert prompted a review of the content in the NHS Pathways system when a patient notifies the call taker that they have a steroid card. It was agreed that, should the patient declare that they have been issued with a steroid card, this would meet the criteria for a “complex call” which would require clinical input.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop and deliver education materials on steroid-dependent patients and adrenal insufficiency, including two clinical alerts.

    Verbatim wording from the response

    “As well as the above several articles and education package have been developed and delivered within the NEAS. These include 2 clinical alerts, which are the primary way NEAS cascades information to its operational teams on matters of clinical practice:”

    Source location

    Response from NE Ambulance Service
    Page 3 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Disseminate an adrenal-crisis training event and additional adrenal-insufficiency and steroid-dependency resources through corporate communications channels.

    Verbatim wording from the response

    “NEAS will, as part of the learning from this tragic event, provide more educational opportunities for its staff including the following:”

    Source location

    Response from NE Ambulance Service
    Page 4 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop a time-critical-medications training module, including steroids, for statutory and mandatory training.

    Verbatim wording from the response

    “▪ We have commenced the development of a training module on time critical medications (which will include Steroids) in our Statutory and Mandatory Training module. This will be included in the Statutory and Mandatory training delivered in 2025/2026.”

    Source location

    Response from NE Ambulance Service
    Page 4 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Include the time-critical-medications module in statutory and mandatory training delivered in 2025/2026.

    Verbatim wording from the response

    “▪ We have commenced the development of a training module on time critical medications (which will include Steroids) in our Statutory and Mandatory Training module. This will be included in the Statutory and Mandatory training delivered in 2025/2026.”

    Source location

    Response from NE Ambulance Service
    Page 4 · response
    Published 14 August 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Roll out a refresher bulletin for Health Advisors on adrenal insufficiency, Addison’s disease and adrenal crisis, and monitor staff completion and understanding.

    Verbatim wording from the response

    “The current version of NHS Pathways does include supporting information for Health Advisors, in respect to adrenal insufficiency, however we do recognise that Health Advisors may benefit from further information about Addison’s disease and specifically adrenal crisis. We are therefore in the process of rolling out a refresher training bulletin confirming the steps to take in these circumstances with some further information relating to the condition. This will be monitored to ensure it has been read and understood by all Health Advisors and those who receive calls via the 111 and/or 999 services. Linking with my response to your second concern, we will support any changes made in the NHS Pathways system alongside any requirements to provide additional information, instruction or training to our call handling teams.”

    Source location

    Response from NE Ambulance Service
    Page 5 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    The North East and North Cumbria Integrated Care Board will respond directly to the Coroner regarding the concerns raised.

    Verbatim wording from the response

    “My regional North West colleagues have also engaged with North East and North Cumbria Integrated Care Board (hereafter “ICB”) on the concerns raised in your Report, who we understand will be responding to the Coroner directly.”

    Source location

    Response from NHS England
    Page 2 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    The Care Quality Commission is responsible for ensuring NHS providers implement the actions required by the National Patient Safety Alert.

    Verbatim wording from the response

    “It is the responsibility of the Care Quality Commission (CQC) to ensure that the actions within an alert have been actioned by NHS provider organisations. However, it is NHS England’s understanding that all Trusts are now compliant with this particular Alert.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    All Trusts are understood to comply with the National Patient Safety Alert on steroid emergency cards.

    Verbatim wording from the response

    “It is the responsibility of the Care Quality Commission (CQC) to ensure that the actions within an alert have been actioned by NHS provider organisations. However, it is NHS England’s understanding that all Trusts are now compliant with this particular Alert.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Education and training of ambulance paramedics is outside the respondent’s remit.

    Verbatim wording from the response

    “Firstly, it is important to note that the education and training of paramedics is not within the remit of AACE or JRCALC.”

    Source location

    Response from Association of Ambulance Chief Executives
    Page 1 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    The Association of Ambulance Chief Executives is the appropriate organisation to provide further information on ambulance-service concerns.

    Verbatim wording from the response

    “I note that you have also sent your Report to the AACE, who would be the appropriate organisation to provide further information on this.”

    Source location

    Response from NHS England
    Page 2 · response
    Published 14 August 2024

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    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Health Advisors are not within the remit to understand complex medical issues such as steroid insufficiency during call triage.

    Verbatim wording from the response

    “Turning towards non-clinical colleagues, specifically Health Advisors, working within the Emergency Operations Centre (EOC) using the NHS Pathways system, currently version 45.2.0. The NHS Pathways system is a national system and has been designed to be used by non-clinicians who ask a series of evidence-based questions to reach an end point. That end point is not a diagnosis, it is just what care and in what timeframe the care is needed. This is then matched to the most appropriate local services who deliver that care. NHS Pathways is not a diagnostic tool, but instead works on the basis of 'ruling out'. This means that questions are asked in order to rule out possible reasons for the patient’s symptoms, until a point where it is safe for the patient to manage their own symptoms with advice or further intervention is needed by a clinician to establish a possible cause.”

    Source location

    Response from NE Ambulance Service
    Page 4 · response
    Published 14 August 2024

    Open published response
  2. Worcestershire

    AI-generated summary

    Michael Leslie PEGG · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Michael Leslie Pegg, who lived with congenital adrenal insufficiency and epilepsy, was admitted to Worcestershire Royal Hospital after two significant seizures and died there on 15 January 2023 following deterioration and pneumonia. The report raised concerns that steroid treatment fell far short of relevant NICE guidelines, that staff awareness and application of the guidelines were insufficient, and that crowded treatment areas created difficulties in providing appropriate care.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Insufficient clinician awareness and ability to apply NICE guidelines for adrenal insufficiency

    Wider context from the report

    “2) Although in this case, I was unable to conclude that the above omissions in steroid treatment probably caused or contributed to Mr. Pegg’s death, it was nonetheless concerning to hear that none of those treating him had sufficient awareness of the NICE Guidelines as to be able to apply them properly in his case. Unless action is taken to ensure clinicians employed by the Trust are aware of, and able to apply these Guidelines, there remains a risk that another patient with adrenal insufficiency may die in similar circumstances; ”

    Source location

    Michael Leslie PEGG · Prevention of Future Deaths report
    Page 2 · concerns

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    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to apply NICE steroid-treatment guidelines for adrenal insufficiency during intercurrent illness

    Wider context from the report

    “1) Over the two days that Mr. Pegg was at Worcestershire Royal Hospital, those treating him failed to apply the NICE guidelines which relate to the treatment of those with adrenal insufficiency conditions who are being treated for intercurrent illness. ████████, who conducted the Trust’s serious incident investigation into these events, told the inquest: “There was a policy in place for administering steroids, as per the 2020 NICE guidelines – this advises: (a) double dosing of oral steroids in cases of intercurrent illness until 48 hours after recovery (also known as Sick Day rule 1); (b) if [the patient has ] significant trauma, prolonged vomiting or diarrhoea, then 100mg IV hydrocortisone [ should be administered ]; (c) if suspected adrenal crisis, 100mg IV hydrocortisone immediately.” In fact, the steroid treatment provided to Mr. Pegg during this admission fell far short of those Guidelines, in that: (a) He only received one double dose of his oral hydrocortisone medication, which he was usually required to take twice a day; (b) He received no doses at all ( double or standard ) of his oral prednisolone medication, which he was usually required to take once a day; (c) Although he did eventually receive a 100mg dose of IV hydrocortisone on 14.1.23, this should have been given much earlier that day when his condition seriously deteriorated. ”

    Source location

    Michael Leslie PEGG · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Use the updated Emergency Department adult patient document, which automatically includes highlighted steroid replacement as a time-critical medication for all adults.

    Verbatim wording from the response

    “several occasions since Mr Pegg’s sad death. Discussions included the importance of the adult patient document in the Emergency Department which was updated in June 2023. This now includes a time critical medications (highlighted steroid replacement) (please see appendix 1 attached). This is automatically included for all adults presenting to the Emergency Department.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Circulate steroid replacement safety materials to Emergency and Medical staff and display them in the Emergency Department handover area.

    Verbatim wording from the response

    “• A “detect and reflect” document and “time critical medication safety flash” have been circulated to all Emergency and Medical staff to raise awareness of the need for steroid replacement therapy (appendix 2, 3). These are displayed in the Emergency Department handover area.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Highlight steroid replacement in Emergency Department handovers and repeat the messaging to maintain medical staff awareness.

    Verbatim wording from the response

    “• Steroid replacement (and other time critical meds) has been highlighted in effective handover in ED in 2023 and will be repeated (appendix 4) to raise and maintain awareness for all medical staff working in the ED.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Incorporate steroids and other time-critical medications into the Emergency Department electronic patient record.

    Verbatim wording from the response

    “• The Trust is due to move to an electronic patient record in the Emergency Department in Autumn 2024 – time critical medications including steroids are due to be incorporated into this.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Participate in the Royal College of Emergency Medicine audit of prescribing and administration of time-critical medicines, including steroids.

    Verbatim wording from the response

    “• The Emergency Departments on both sites are participating in a Royal College of Emergency Medicine audit looking at the prescribing and administration of time critical medicines, including steroids. This audit will provide a “benchmark” for the Trust and also highlight areas where further improvement is required. The audit is still in data collection phase but results will be available later in the year.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Have the Acting Chief Medical Officer highlight steroid replacement during induction for new doctors rotating into the hospitals.

    Verbatim wording from the response

    “• The Acting Chief Medical Officer will be attending the Induction for new doctors in August in order to highlight this area of focus for the Trust for all junior doctors rotating into our hospitals.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

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    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Prioritise adrenal insufficiency and steroid replacement for Medical Examiner review, triggering further case review when concerns are identified.

    Verbatim wording from the response

    “• The Medical Examiners, at the request of the Trust, are working with Adrenal Insufficiency/Steroid Replacement as one of their high priority conditions which means that any concerns identified with steroid replacement will trigger further case review. The focus therefore remains on this area and will continue to be so until we are fully assured that our processes for identifying and managing this condition are effective.”

    Source location

    Response from Worcestershire Acute Hospitals NHS Trust
    Page 2 · response
    Published 7 June 2024

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Publish guidance for preventing and managing adrenal insufficiency emergencies in adults.

    Verbatim wording from the response

    “NHS England has also worked closely with the Society for Endocrinology and the Royal College of Physicians on the issue of under-recognition and treatment of adrenal insufficiency or crisis. This culminated in the publication of ‘Guidance for the prevention and emergency management of adult patients with adrenal insufficiency’ in July 2020, which outlines the causes of adrenal insufficiency, groups at risk of an adrenal crisis, emergency management and management for surgical procedures. As a result of work in this area, a new NHS Steroid Emergency Card was developed, to be carried by patients at risk of adrenal crisis and ensure the prompt delivery of steroids to those patients presenting within an emergency or acute medicine setting.”

    Source location

    Response from NHS England
    Page 1 · response
    Published 7 June 2024

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop the NHS Steroid Emergency Card for patients at risk of adrenal crisis.

    Verbatim wording from the response

    “NHS England has also worked closely with the Society for Endocrinology and the Royal College of Physicians on the issue of under-recognition and treatment of adrenal insufficiency or crisis. This culminated in the publication of ‘Guidance for the prevention and emergency management of adult patients with adrenal insufficiency’ in July 2020, which outlines the causes of adrenal insufficiency, groups at risk of an adrenal crisis, emergency management and management for surgical procedures. As a result of work in this area, a new NHS Steroid Emergency Card was developed, to be carried by patients at risk of adrenal crisis and ensure the prompt delivery of steroids to those patients presenting within an emergency or acute medicine setting.”

    Source location

    Response from NHS England
    Page 1 · response
    Published 7 June 2024

    Open published response
  3. Liverpool and the Wirral

    AI-generated summary

    Amirah KHALIFA · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Amirah Khalifa was admitted to hospital in December 2022 after feeling generally unwell and deteriorated despite active treatment, dying on 31 January 2023. The report states that multiple organ failure caused by sepsis and intestinal haemorrhage was more likely than not related to long-term steroid therapy. Principal concerns included failures to document, monitor and review the steroid treatment, recognise its complications, and ensure that its clinical indication and intended duration were communicated to primary care; the SCR also did not automatically flag long-term steroid use or record the clinical indication for prescribed drugs.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure of the SCR model to automatically flag long-term steroid use for appropriate monitoring

    Wider context from the report

    “The current SCR model does not appear to automatically flag drugs such as steroids, which are known to have potentially fatal side effects if used for the long term without appropriate monitoring. It is understood that some drugs do have these flags, but that steroids do not. ”

    Source location

    Amirah KHALIFA · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
  4. Worcestershire

    AI-generated summary

    DAVID ERNEST MASON · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    David Ernest Mason, aged 82, fell at home on 5 March 2022, fractured his hip and was taken to hospital after an ambulance delay. He had Addison’s disease and died in the early hours of 7 March 2022 after developing an acute adrenal crisis. The principal concerns were that clinicians and ambulance staff did not recognise the need for additional steroid replacement after trauma and physiological stress, and that relevant clinical guidance, call-handler pathways and documentation prompts did not sufficiently address this risk.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Call-handler pathway failing to consider adrenal crisis risk after trauma

    Wider context from the report

    “2) Evidence heard at the inquest demonstrated that when information is given to an EOC (emergency operations centre) call-handler at WMAS that a patient has a diagnosis of Addison’s disease and has suffered trauma, the call-handler question pathway (which, the inquest heard, is based on a computer-programmed logarithm (designed by NHS Digital, now part of NHS England)) does not go on to consider the risk of adrenal insufficiency and the requirement for replacement steroid therapy to commence immediately. This appears to be potentially relevant both in respect of whether time-critical steroid treatment may be required (and thus for a holistic consideration of call categorisation) and safety-netting advice that should be given (for additional doses of steroid medication to be taken by the patient, prior to any ambulance arrival). Safety-netting advice takes on even greater significance in the current climate, where healthcare demand and pressures on capacity are often causing severe delays in ambulance attendance. Evidence heard at the inquest confirmed that the position is different if information is given that the patient is medically unwell, particularly if concerns of a cardiac nature are present or adrenal insufficiency may be the direct cause of current illness, with the call-handler question pathway then going on to consider the risk of adrenal insufficiency. Currently there is a cohort of patients (which included Mr Mason) whose risk of developing an adrenal crisis is not being considered by call-handlers at WMAS. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 3 · concerns

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    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    National treatment guidance failing to emphasise replacement steroid therapy after trauma or physiological stress

    Wider context from the report

    “1) The relevant treatment guideline disclosed by WAHT (‘Guideline for the management of adrenal insufficiency in adults’) very much focuses on presentations of acute adrenal crisis and procedure-based/perioperative situations, and (save for a small section containing ‘sick day’ rules) does not emphasise that replacement steroid therapy must be given to patients with adrenal insufficiency who have suffered trauma or physiological stress. Evidence heard at the inquest suggested that this internal Trust guideline (and, one assumes, other such guidelines in other acute trusts in the country) is based upon various pieces of national guidance. It is my understanding that a new guideline in respect of managing the treatment of adrenal insufficiency is currently being developed by NICE. Consideration of these matters should be included as part of guideline development. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 4 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure of acute hospital clinicians to recognise the need for replacement steroid therapy after trauma or physiological stress

    Wider context from the report

    “1) Evidence heard at the inquest demonstrated that no clinician involved in providing care to Mr Mason (in both the emergency department and the surgical trauma department) appreciated that, as someone who had Addison’s disease and who had suffered the trauma of a fall, long lie and a fractured hip, Mr Mason required additional replacement steroid therapy, to prevent the development of an acute adrenal crisis. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Absence of adrenal insufficiency prompts in emergency department and clerking documentation

    Wider context from the report

    “4) Evidence heard at the inquest confirmed that no prompts exist on emergency department/clerking documentation at WAHT for clinicians to check whether a patient suffers from adrenal insufficiency. Although the inquest was informed that changes have been made in this regard by WAHT to some peri-operative patient documentation, the National Patient Safety Alert (NatPSA/2020/005/NHSPS) requires acute trusts to review admission/assessment/clerking documentation to ensure such prompts are included. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 5 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Guideline failing to emphasise replacement steroid therapy after trauma or physiological stress

    Wider context from the report

    “2) The relevant internal Trust guideline disclosed by WAHT (‘Guideline for the management of adrenal insufficiency in adults’) very much focuses on presentations of acute adrenal crisis and procedure-based/perioperative situations, and (save for a small section containing ‘sick day’ rules, which are on the same page as advice to patients and families for long-term condition management) does not emphasise that replacement steroid therapy must be given to patients with adrenal insufficiency who have suffered trauma or physiological stress. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 4 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Insufficient clinician knowledge of adrenal insufficiency and replacement steroid therapy

    Wider context from the report

    “3) Evidence heard at the inquest (relating to the trauma/surgical department at WAHT) suggested that it is likely that many clinicians (including at consultant level) do not have a well-developed understanding of adrenal insufficiency and the crucial importance of administering replacement steroid therapy to patients who, although not presenting as acutely unwell, are at risk of suffering an adrenal crisis. ”

    Source location

    DAVID ERNEST MASON · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Liaise with JRCALC to align ambulance protocols and clarify additional oral or intramuscular hydrocortisone for trauma or injury.

    Verbatim wording from the response

    “The Society for Endocrinology will have opportunity to review this when it is shared with stakeholders and provide comments. Also, members of the Society for Endocrinology are on the committee writing the guidelines and will ensure these topics are covered. In terms of Ambulance service, JRCALC has protocols advising on the management of patients with adrenal insufficiency. ████████ is liaising with them, at present and we will ensure all protocols align and are clear about the need to give additional oral or IM hydrocortisone in trauma/injury. JRCALC guidelines state anyone can give IM hydrocortisone and we are aware that there is an issue around paramedics and technicians being reminded both groups can administer emergency treatment. This is important as different types of ambulance have different health care professionals working on them.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Work with ambulance, 999 and 111 services through NHSE to include steroid emergency information in call-handler triage and support category 2 ambulance dispatch.

    Verbatim wording from the response

    “In terms of the NHSE steroid emergency card, the wording states injury/shock. We will continue our work with both ambulance services and 999/111 services via NHSE patient safety team to ensure this is on the triage information to call handlers so a category 2 ambulance can be sent. All ambulances carry hydrocortisone, and both paramedics and ambulance technicians are able to administer IM hydrocortisone so this should not be a blocker to administration. JRCALC may be able to address this in their guidelines. It is possible thatmore work is needed to disseminate the information available and we can continue working with RCP Patient Safety Committee and NHSE Patient Safety team in this regard. We will also update our resources accordingly.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Raise the NHS Pathways concern about adrenal-insufficiency risks following trauma on the clinical concern log.

    Verbatim wording from the response

    “Response Calls to 999 are assessed in accordance with the Department of Health National Guidelines using a process called NHS Pathways (NHSP).”

    Source location

    Response from West Midlands Ambulance Service
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Engage stakeholders and monitor emerging evidence and guidelines on emergency steroid replacement in pre-hospital care.

    Verbatim wording from the response

    “However, having learned of this case, NHS Pathways will engage with its stakeholders and monitor emerging evidence and guidelines with respect to emergency steroid replacement therapy in the pre-hospital setting, with a view to making system changes where appropriate in accordance with the governance framework. If it is established that system-wide changes are required, NHS Pathways will work closely with colleagues in the ambulance sector to ensure safety-netting advice is appropriate.”

    Source location

    Response from NHS England
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Engage Medical Priority Dispatch System suppliers to review their processes for assessing adrenal insufficiency.

    Verbatim wording from the response

    “NHS England will also engage with Medical Priority Dispatch System, the suppliers of the alternative telephone and digital triage system used by ambulance services in England, to review their processes for assessing adrenal insufficiency.”

    Source location

    Response from NHS England
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Ensure trauma and physiological stress topics are covered in the NICE adrenal insufficiency guideline.

    Verbatim wording from the response

    “Trauma and physiological stress are within scope for the NICE guideline on adrenal insufficiency currently in development. There is representation from paramedics, Emergency Medicine, General Practice and lay members on the committee so the guidelines will cover pre hospital care. Once guidelines are published there is a plan for another round of communications to disseminate the information.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Publish guidance for preventing and managing adult adrenal insufficiency emergencies.

    Verbatim wording from the response

    “NHS England has worked closely with the Society for Endocrinology and the Royal College of Physicians on the issue of under-recognition and treatment of adrenal insufficiency or crisis. This culminated in the publication of ‘Guidance for the prevention and emergency management of adult patients with adrenal insufficiency’ in July 2020, which outlines the causes of adrenal insufficiency, groups at risk of an adrenal crisis, emergency management and management for surgical procedures. As a result of work in this area, a new NHS Steroid Emergency Card was developed, to be carried by patients at risk of adrenal crisis and ensure the prompt delivery of steroids to those patients presenting with adrenal insufficiency or acute medicine setting.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Revise JRCALC guidance to emphasize steroid administration after trauma or physiological stress.

    Verbatim wording from the response

    “Your first matter of concern relates to our ‘JRCALC guidance’ not being sufficiently clear that patients who may have suffered trauma or physiological stress also require steroid treatment, to prevent an adrenal crisis. The JRCALC guidelines have been in existence since the 1990’s but it was only in 2022 that we decided that a standalone guideline for steroid dependent patients was needed. We have decided that the wording and emphasis on administering steroids to patients who suffer trauma or physiological stress could have more emphasis placed on it, so we are now in the process of revising our guidance.”

    Source location

    Response from Association of Ambulance
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop steroid-dependent patient guidance with input from patient representatives and clinical advisers.

    Verbatim wording from the response

    “Your first matter of concern relates to our ‘JRCALC guidance’ not being sufficiently clear that patients who may have suffered trauma or physiological stress also require steroid treatment, to prevent an adrenal crisis. The JRCALC guidelines have been in existence since the 1990’s but it was only in 2022 that we decided that a standalone guideline for steroid dependent patients was needed. We have decided that the wording and emphasis on administering steroids to patients who suffer trauma or physiological stress could have more emphasis placed on it, so we are now in the process of revising our guidance.”

    Source location

    Response from Association of Ambulance
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Cover identification, emergency management and prevention of adrenal crisis during trauma and other physiological stress in the new guideline.

    Verbatim wording from the response

    “We have reflected on the circumstances surrounding Mr Mason’s death, and the concerns raised in your report. We note your suggestion that the issues raised in your report should be considered in the development of our new guideline on adrenal insufficiency, particularly that replacement steroid therapy must be given to patients with adrenal insufficiency who have suffered trauma or physiological stress.”

    Source location

    Response from NICE
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Include two paramedic co-optees and relevant emergency-care health professionals on the adrenal insufficiency guideline committee.

    Verbatim wording from the response

    “I can confirm that the scope of this guideline covers adrenal crisis including identification and emergency management and preventing adrenal crisis during periods of physiological stress, which includes trauma. Membership of the guideline committee recruited for this topic includes two paramedic co-optees, as well as health professionals who see people with adrenal crisis or who are at risk of adrenal crisis in the emergency department.”

    Source location

    Response from NICE
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Continue liaising with NHSE and the Royal College of Emergency Medicine to support appropriate additional hydrocortisone for patients with adrenal insufficiency.

    Verbatim wording from the response

    “We are aware that, in the current climate with pressures on ambulance services and emergency departments, there may be delays in patients with adrenal insufficiency being managed appropriately. We will continue to liaise with the NHSE patient safety team and Royal College of Emergency Medicine to ensure that patients with adrenal insufficiency are given additional hydrocortisone in the appropriate way to prevent further deaths.”

    Source location

    Response from Society for Endocrinology
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Provide individual feedback and require reflection by clinicians involved in the case.

    Verbatim wording from the response

    “1. In order to raise awareness and educate clinicians, the following actions have been taken. Individual feedback was given and reflection undertaken by clinicians involved in July 2022 (appendix 1). On the 9th May 2023 at the Trauma & Orthopaedic (T&O) Governance meeting attended by 33 multidisciplinary staff including T&O Consultants this case was discussed and reflected upon (appendix 2). A teaching session was delivered by the Deputy Chief Medical Officer to 40+ Surgical trainees at a Regional Teaching Session on the 9th May 2023 (appendix 3). A teaching session highlighting the risk of adrenal insufficiency for T&O Junior Doctors delivered by a consultant Anaesthetist is now given three times per year as part of the induction programme (appendix 4).”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Deliver teaching on the case and adrenal insufficiency risks to surgical trainees at a regional teaching session.

    Verbatim wording from the response

    “1. In order to raise awareness and educate clinicians, the following actions have been taken. Individual feedback was given and reflection undertaken by clinicians involved in July 2022 (appendix 1). On the 9th May 2023 at the Trauma & Orthopaedic (T&O) Governance meeting attended by 33 multidisciplinary staff including T&O Consultants this case was discussed and reflected upon (appendix 2). A teaching session was delivered by the Deputy Chief Medical Officer to 40+ Surgical trainees at a Regional Teaching Session on the 9th May 2023 (appendix 3). A teaching session highlighting the risk of adrenal insufficiency for T&O Junior Doctors delivered by a consultant Anaesthetist is now given three times per year as part of the induction programme (appendix 4).”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Provide recurring adrenal insufficiency teaching to Trauma and Orthopaedic junior doctors through induction, three times annually.

    Verbatim wording from the response

    “1. In order to raise awareness and educate clinicians, the following actions have been taken. Individual feedback was given and reflection undertaken by clinicians involved in July 2022 (appendix 1). On the 9th May 2023 at the Trauma & Orthopaedic (T&O) Governance meeting attended by 33 multidisciplinary staff including T&O Consultants this case was discussed and reflected upon (appendix 2). A teaching session was delivered by the Deputy Chief Medical Officer to 40+ Surgical trainees at a Regional Teaching Session on the 9th May 2023 (appendix 3). A teaching session highlighting the risk of adrenal insufficiency for T&O Junior Doctors delivered by a consultant Anaesthetist is now given three times per year as part of the induction programme (appendix 4).”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Share a Lesson of the Week on adrenal insufficiency through governance teams and Trust communication and incident-management channels.

    Verbatim wording from the response

    “A Lesson of the Week was shared on 25th May 2023 (appendix 5), with Governance teams to disseminating it through Divisions, in the Trust “Worcestershire Weekly”, Datix Incident management system and the Trust Intranet page.”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Amend the Trust guideline to advise on additional steroid replacement for admitted Emergency Department patients at risk from physiological stress and pain.

    Verbatim wording from the response

    “2. The Trust guideline, based on National guidance, has been amended to include clear advice for all patients in the Emergency Departments who require admission (appendix 6). Following discussion with our Endocrinology and Emergency Department teams, it was felt that this would be the most effective way of ensuring that clinicians were aware of the need for additional steroid replacement therapy for patients at risk of adrenal crisis due to physiological stress and pain.”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Implement Emergency Department admission-document prompts for time-critical steroid medications and consideration of increased steroid doses.

    Verbatim wording from the response

    “4. Changes have been made to the ED admission documents, implemented 6th June 2023, to include prompts on time critical medications, including steroids, and to consider increasing the dose of steroids (appendix 7). The T&O admission document, as discussed at the Inquest, was updated in October 2022 to include Steroid Management prompts (appendix 8).”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Update the Trauma and Orthopaedic admission document to include steroid-management prompts.

    Verbatim wording from the response

    “4. Changes have been made to the ED admission documents, implemented 6th June 2023, to include prompts on time critical medications, including steroids, and to consider increasing the dose of steroids (appendix 7). The T&O admission document, as discussed at the Inquest, was updated in October 2022 to include Steroid Management prompts (appendix 8).”

    Source location

    Response from Worcestershire Acute Hospitals
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop the NHS Steroid Emergency Card for patients at risk of adrenal crisis.

    Verbatim wording from the response

    “NHS England has worked closely with the Society for Endocrinology and the Royal College of Physicians on the issue of under-recognition and treatment of adrenal insufficiency or crisis. This culminated in the publication of ‘Guidance for the prevention and emergency management of adult patients with adrenal insufficiency’ in July 2020, which outlines the causes of adrenal insufficiency, groups at risk of an adrenal crisis, emergency management and management for surgical procedures. As a result of work in this area, a new NHS Steroid Emergency Card was developed, to be carried by patients at risk of adrenal crisis and ensure the prompt delivery of steroids to those patients presenting with adrenal insufficiency or acute medicine setting.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Issue the National Patient Safety Alert requiring providers to prompt checks for adrenal-crisis risk and Steroid Emergency Cards.

    Verbatim wording from the response

    “The work above also resulted in the publication of the National Patient Safety Alert (NatPSA), mentioned in your report, which includes the specific action that ‘Providers that treat patients with acute physical illness or trauma, or who may require emergency or elective surgical or other invasive procedures, including day patients, should review their admission/assessment/examination/clerking documentation to ensure it includes prompts to check for risk of adrenal crisis and to establish if the patient has a Steroid Emergency Card.’ Trusts were expected to implement actions around this specific alert by 13 May 2021.”

    Source location

    Response from NHS England
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Disseminate information through another communications round after the NICE guideline is published.

    Verbatim wording from the response

    “Trauma and physiological stress are within scope for the NICE guideline on adrenal insufficiency currently in development. There is representation from paramedics, Emergency Medicine, General Practice and lay members on the committee so the guidelines will cover pre hospital care. Once guidelines are published there is a plan for another round of communications to disseminate the information.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Update Society resources on adrenal insufficiency and emergency hydrocortisone.

    Verbatim wording from the response

    “In terms of the NHSE steroid emergency card, the wording states injury/shock. We will continue our work with both ambulance services and 999/111 services via NHSE patient safety team to ensure this is on the triage information to call handlers so a category 2 ambulance can be sent. All ambulances carry hydrocortisone, and both paramedics and ambulance technicians are able to administer IM hydrocortisone so this should not be a blocker to administration. JRCALC may be able to address this in their guidelines. It is possible thatmore work is needed to disseminate the information available and we can continue working with RCP Patient Safety Committee and NHSE Patient Safety team in this regard. We will also update our resources accordingly.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Maintain a webpage providing resources to help healthcare teams develop adrenal insufficiency management resources.

    Verbatim wording from the response

    “In order to support health and care providers, the Society for Endocrinology has set up a webpage with resources to help health care teams develop resources to support management of adrenal insufficiency. We will review this once NICE guidelines are written and ensure that pre-hospital care is covered more clearly. We would be happy to work with Worcestershire Acute Hospitals NHS Trust to review their materials if helpful.”

    Source location

    Response from Society for Endocrinology
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Communicate updated adrenal-crisis and steroid-dependent-patient guidance to staff through clinical times and clinical notices.

    Verbatim wording from the response

    “Response In 2017 there was an update in the Joint Royal Colleges Ambulance Liaison Committee (JRCALC) guidance emphasising the increased usage of Hydrocortisone for patients with adrenal crisis, including a further note stating if in doubt administer Hydrocortisone. This was communicated to all staff through the clinical times edition 30. The clinical times is an internal quarterly briefing which provides all staff with new or updated clinical guidance.”

    Source location

    Response from West Midlands Ambulance Service
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Provide clinicians with access to JRCALC guidance through individual licenses and the JRCALC Plus app.

    Verbatim wording from the response

    “All WMAS clinicians are given access to the JRCALC guidelines through individual licenses for the JRCALC Plus app. Staff are also provided a Trust personal issue Ipad and the app can be accessed through this device, or there is the option for the app to be also downloaded on other devices such as personal smart phones if they so choose so. This allows clinicians to access the guidelines whilst at the patient side.”

    Source location

    Response from West Midlands Ambulance Service
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Disseminate relevant external clinical guidance, including steroid emergency-card guidance, through weekly staff briefings.

    Verbatim wording from the response

    “As well as the above a number of articles have been run within the WMAS weekly briefing. The weekly briefing which is emailed to all WMAS employees provides all the latest information about WMAS and any changes to guidance that have been made by external bodies in relation to clinical practice that must be considered. An example of such is below:”

    Source location

    Response from West Midlands Ambulance Service
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Publish an in-depth clinical-times article to improve clinicians’ knowledge of adrenal insufficiency and replacement steroid therapy.

    Verbatim wording from the response

    “Response Following review of the serious incident investigation and receipt of the PFD we agree a recommendation should have been made to raise awareness and improve clinicians knowledge of adrenal insufficiency and the importance of considering administering replacement steroid therapy. Therefore we have reemphasised the care of the steroid dependant patient with an in depth article with appropriate links for further reading and education, publishing the below in the clinical times on the 12th of May 2023.”

    Source location

    Response from West Midlands Ambulance Service
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Ambulance hydrocortisone availability and authorised personnel should not prevent administration during trauma or injury.

    Verbatim wording from the response

    “In terms of the NHSE steroid emergency card, the wording states injury/shock. We will continue our work with both ambulance services and 999/111 services via NHSE patient safety team to ensure this is on the triage information to call handlers so a category 2 ambulance can be sent. All ambulances carry hydrocortisone, and both paramedics and ambulance technicians are able to administer IM hydrocortisone so this should not be a blocker to administration. JRCALC may be able to address this in their guidelines. It is possible thatmore work is needed to disseminate the information available and we can continue working with RCP Patient Safety Committee and NHSE Patient Safety team in this regard. We will also update our resources accordingly.”

    Source location

    Response from Society for Endocrinology
    Page 1 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    WMAS cannot change the nationally required NHS Pathways triage system used to assess 999 calls.

    Verbatim wording from the response

    “Response Calls to 999 are assessed in accordance with the Department of Health National Guidelines using a process called NHS Pathways (NHSP).”

    Source location

    Response from West Midlands Ambulance Service
    Page 3 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Existing NHS Pathways design is considered sufficient because extra adrenal-insufficiency questioning could delay care or create confusion.

    Verbatim wording from the response

    “The majority of calls taken using NHS Pathways are handled by a highly trained but non-clinical Health Advisor. Health Advisors (as per the NHS Pathways Provider Licence) should have access to support from clinicians to support safe call-handling. Even though thorough training is provided, it is not within the remit of the Health Advisor to be trained in, or understand more complex medical elements, such as in this case. Indeed, such enquiry and added confusion delays the management of the case and triaging process. It is for these reasons that questions on past medical history or pharmacology are utilised sparingly across the system, and only where it is deemed that a clear understanding can be sought.”

    Source location

    Response from NHS England
    Page 2 · response
    Published 26 April 2023

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    AACE has no responsibility for changing the NHS Pathways system used to assess 999 calls in the West Midlands.

    Verbatim wording from the response

    “With regard to your second matter of concern about the advice given in ambulance control centres to people who call 999. Calls to 999 in the West Midlands region are assessed in accordance with the Department of Health National Guidelines using a process called NHS Pathways (NHSP) and therefore we have no responsibility for making changes to this system. We are aware from West Midlands ambulance service that the matter has been raised with NHSP. We are however aware of the development of an educational e learning package for call handlers so they have a better understanding and awareness of Addison’s disease and steroid dependent patients. The package will be trialled in Yorkshire and is being developed in conjunction with The Pituitary Foundation.”

    Source location

    Response from Association of Ambulance
    Page 1 · response
    Published 26 April 2023

    Open published response
  5. Plymouth, Torbay and South Devon

    AI-generated summary

    Terence Bradfield · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Terence Bradfield entered Derriford Hospital on 1 December 2013 with gastric bleeding and died on 17 December 2013, primarily from the consequences of his gastrointestinal bleed. The report raised concerns that his long-term steroid medication was not given or adequately managed, including when he was vomiting, and about staff training and the absence of policies for steroid management and “Nil by Mouth” patients with co-morbidities.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to provide stress-dose steroids

    Wider context from the report

    “(1) They are : 1. Mr. Bradfield was not given his steroids on 2.12.13 2. Mr. Bradfield was not prescribed intravenous hydrocortisone on 4th and 5th December 2013 when Mr. Bradfield had reported vomiting 3. Mr. Bradfield was not put on a stress dose of steroids whilst in Derriford hospital 4. The awareness and training of staff on the issue of steroid management. 5. The lack of a policy on the administration of steroids generally and their use in situations where a number of co – morbidities are present despite this death having arisen in 2013. 6. The training and awareness of staff on the meaning of “Nil by Mouth “ in patients who are suffering from a number of co –morbidities and are on important prescribed medication which needs to be taken regularly notwithstanding any planned necessary procedures . ”

    Source location

    Terence Bradfield · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Inadequate staff awareness and training on steroid management

    Wider context from the report

    “(1) They are : 1. Mr. Bradfield was not given his steroids on 2.12.13 2. Mr. Bradfield was not prescribed intravenous hydrocortisone on 4th and 5th December 2013 when Mr. Bradfield had reported vomiting 3. Mr. Bradfield was not put on a stress dose of steroids whilst in Derriford hospital 4. The awareness and training of staff on the issue of steroid management. 5. The lack of a policy on the administration of steroids generally and their use in situations where a number of co – morbidities are present despite this death having arisen in 2013. 6. The training and awareness of staff on the meaning of “Nil by Mouth “ in patients who are suffering from a number of co –morbidities and are on important prescribed medication which needs to be taken regularly notwithstanding any planned necessary procedures . ”

    Source location

    Terence Bradfield · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report
  6. Wiltshire and Swindon

    AI-generated summary

    Robin Keith Brett · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Robin Keith Brett, an 18-year-old man with congenital adrenal hyperplasia, died on 14 June 2014 after being admitted with severe constipation and an addisonian crisis. He did not receive his prescribed steroids, and the concerns identified were that nursing staff failed to notice the missed dose and that prescribing systems lacked an alert for patients taking long-term steroids.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to detect missed steroid doses

    Wider context from the report

    “This patient was prescribed steroids appropriately but the nursing staff failed to notice a dose of steroids had been missed. There is no system on the paper drug chart or the electronic prescribing system for alerting medical staff to patients being on long term steroids. ”

    Source location

    Robin Keith Brett · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of alerts identifying patients on long-term steroids

    Wider context from the report

    “This patient was prescribed steroids appropriately but the nursing staff failed to notice a dose of steroids had been missed. There is no system on the paper drug chart or the electronic prescribing system for alerting medical staff to patients being on long term steroids. ”

    Source location

    Robin Keith Brett · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
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Data last updated 7 September 2026