Recurring concern

Failure to identify clinically significant medication risks

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First reported 30 Jul 2013•Latest report 3 Jun 2026

Definition

What this concern includes

Includes failures in medication review, reconciliation, prescribing or screening that concern recognising the clinical significance of a medicine, contraindication, interaction, toxicity, side-effect or existing medication.

Not included

  • Excludes failures to administer, monitor or supply medication where the concern is not specifically the identification of medication-related risk.
  • Excludes illicit or general drug-use hazards not tied to a medication-safety control.
  • Excludes generic failures to recognise symptoms or deterioration unless the report explicitly links them to medication-related risk.
  • Excludes generic communication, documentation or staffing deficiencies that are not dedicated to identifying medication risks.
Reports
54

Distinct published reports

Individual concerns
58

A report can raise multiple concerns

Date range
2013–2026

First to latest report issue date

Stated actions
100

Described in published responses

Reports over time

Reports over time

Reports about this concern issued each year.

* 2026 is projected from reports observed to 7 Sep 2026.

Most frequent recipients

Most frequent recipients

Reports about this concern sent to each recipient.

Department of Health and Social Care8
NHS England6
NHS Greater Manchester Integrated Care Board5
Care Quality Commission4
Medicines and Healthcare products Regulatory Agency4
NHS Surrey and Sussex Integrated Care Board3
Royal College of General Practitioners3
Betsi Cadwaladr University LHB2
General Medical Council2
Greater Manchester Health and Social Care Partnership2
Herefordshire and Worcestershire Health and Care NHS Trust2
Nursing and Midwifery Council2
Royal College of Psychiatrists2
Adelaide Medical Centre, London1
Alvaston Medical Centre1

Concerns and responses across reports

Only concerns grouped under this recurring concern are included. Select any concern, action or position to view the source wording.

  1. Derby and Derbyshire

    AI-generated summary

    Maria Susan McGAURAN · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Maria Susan McGAURAN had been prescribed codeine and citalopram and died at home on 28 November 2018 due to the combined toxicity of those medications. Concerns were raised that she had hoarded and taken medication erratically, but the Surgery did not undertake a requested medication review or consider alternative pain management earlier.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to undertake a medication review in response to known excessive, hoarded and erratic medication use

    Wider context from the report

    “Ms McGauran had over several years been known to take excessive amounts of her codeine prescription medication. She had a history of hoarding medication and taking her medication erratically. Her family raised concerns with the Surgery as to her reliance on several differing medications. They requested that a review of her medications be undertaken. No such review was undertaken. The Surgery could have considered alternative pain management aids at an earlier stage (such as the Fentanyl patches considered only 1 month before death i.e. in October 2018) so as to prevent the risks of overdose. ”

    Source location

    Maria Susan McGAURAN · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Recruit two clinical pharmacists to support patient medication reviews.

    Verbatim wording from the response

    “1. Taking advantage of the expanding job roles within primary care, over the period January to February 2021, Alvaston Medical Centre recruited two clinical pharmacists to undergo patient medication reviews. The clinical pharmacist's area of professional expertise means they are ideally suited to conducting structured medication reviews of patients – including extensive knowledge of controlled drugs. As part of the medication review, they explore the patient’s compliance and understanding of their medication, along with addressing other concerns within their remit.”

    Source location

    2022-0098-Response-from-Alvaston-Medical-Centre_Published
    Page 1 · response
    Published 26 April 2022

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Conduct structured, holistic medication reviews covering compliance, understanding, social history, lifestyle and medication changes.

    Verbatim wording from the response

    “1. Taking advantage of the expanding job roles within primary care, over the period January to February 2021, Alvaston Medical Centre recruited two clinical pharmacists to undergo patient medication reviews. The clinical pharmacist's area of professional expertise means they are ideally suited to conducting structured medication reviews of patients – including extensive knowledge of controlled drugs. As part of the medication review, they explore the patient’s compliance and understanding of their medication, along with addressing other concerns within their remit.”

    Source location

    2022-0098-Response-from-Alvaston-Medical-Centre_Published
    Page 1 · response
    Published 26 April 2022

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Prevent high-risk scheduled drugs from forming part of repeat prescriptions wherever possible.

    Verbatim wording from the response

    “3. Alvaston has also made it good practice, to ensure wherever possible, any high risk scheduled drugs do not form part of the repeat prescription. Furthermore, we have a robust system in place to ensure the prescribing of medications is not automatically ordered too far in advance of their due date. This reduces the risk of any patient's 'stock-piling' medication. This is an ongoing project that is constantly being reviewed and refined, and we continue to further assess which areas or medications would benefit from additional surveillance during the prescribing and issuing of the prescription.”

    Source location

    2022-0098-Response-from-Alvaston-Medical-Centre_Published
    Page 1 · response
    Published 26 April 2022

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Prevent prescriptions from being ordered automatically too far in advance of their due dates.

    Verbatim wording from the response

    “3. Alvaston has also made it good practice, to ensure wherever possible, any high risk scheduled drugs do not form part of the repeat prescription. Furthermore, we have a robust system in place to ensure the prescribing of medications is not automatically ordered too far in advance of their due date. This reduces the risk of any patient's 'stock-piling' medication. This is an ongoing project that is constantly being reviewed and refined, and we continue to further assess which areas or medications would benefit from additional surveillance during the prescribing and issuing of the prescription.”

    Source location

    2022-0098-Response-from-Alvaston-Medical-Centre_Published
    Page 1 · response
    Published 26 April 2022

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Continue assessing medications and prescribing areas that would benefit from additional surveillance.

    Verbatim wording from the response

    “3. Alvaston has also made it good practice, to ensure wherever possible, any high risk scheduled drugs do not form part of the repeat prescription. Furthermore, we have a robust system in place to ensure the prescribing of medications is not automatically ordered too far in advance of their due date. This reduces the risk of any patient's 'stock-piling' medication. This is an ongoing project that is constantly being reviewed and refined, and we continue to further assess which areas or medications would benefit from additional surveillance during the prescribing and issuing of the prescription.”

    Source location

    2022-0098-Response-from-Alvaston-Medical-Centre_Published
    Page 1 · response
    Published 26 April 2022

    Open published response
  2. Manchester South

    AI-generated summary

    Elaine Michelle Inns · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Elaine Michelle Inns was found dead at her home on 18 January 2021. The inquest heard that she continued to be prescribed powerful painkillers despite significant alcohol use and use of liquid morphine without clearly following dosage instructions; the medical cause of death involved the combined toxic effects of ethanol and prescribed medicines.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to account for significant alcohol use when prescribing powerful painkillers

    Wider context from the report

    “The inquest heard that Elaine Inns continued to be prescribed a combination of medication including a number of powerful painkillers although it was well understood that she was also using alcohol in significant quantities whilst taking her prescribed medication. The evidence before the court also indicated that she would use the prescribed liquid morphine without clearly following the recommended dosage instructions. She continued to be prescribed it. ”

    Source location

    Elaine Michelle Inns · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Share up-to-date opiate prescribing guidance across Stockport practices.

    Verbatim wording from the response

    “Having reviewed this overall investigation and the circumstances which led to the issue of your Regulation 28 report, I reach the conclusion that the key issue is the prescribing of opiates and I am satisfied that appropriate steps have been taken to ensure the safe prescribing of opiate medication at the individual practice and across the wider Stockport GP community. I will ensure that the most up to date opiate prescribing guidance is shared across our practices and work with colleagues across our system to ensure adherence to best practice guidance.”

    Source location

    2021-0285-Response-from-Stockport-CCG_Published.pdf
    Page 4 · response
    Published 2 September 2021

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Work with system colleagues to ensure adherence to best-practice opiate prescribing guidance.

    Verbatim wording from the response

    “Having reviewed this overall investigation and the circumstances which led to the issue of your Regulation 28 report, I reach the conclusion that the key issue is the prescribing of opiates and I am satisfied that appropriate steps have been taken to ensure the safe prescribing of opiate medication at the individual practice and across the wider Stockport GP community. I will ensure that the most up to date opiate prescribing guidance is shared across our practices and work with colleagues across our system to ensure adherence to best practice guidance.”

    Source location

    2021-0285-Response-from-Stockport-CCG_Published.pdf
    Page 4 · response
    Published 2 September 2021

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Existing prescribing safeguards are considered sufficient to ensure safe opiate prescribing across the individual practice and wider Stockport GP community.

    Verbatim wording from the response

    “Having reviewed this overall investigation and the circumstances which led to the issue of your Regulation 28 report, I reach the conclusion that the key issue is the prescribing of opiates and I am satisfied that appropriate steps have been taken to ensure the safe prescribing of opiate medication at the individual practice and across the wider Stockport GP community. I will ensure that the most up to date opiate prescribing guidance is shared across our practices and work with colleagues across our system to ensure adherence to best practice guidance.”

    Source location

    2021-0285-Response-from-Stockport-CCG_Published.pdf
    Page 4 · response
    Published 2 September 2021

    Open published response
  3. Norfolk

    AI-generated summary

    Ben Buster KING · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Ben Buster KING was detained under the Mental Health Act at Jeesal Cawston Park and died in hospital on 29 July 2020 after becoming unwell following respiratory problems and receiving sedative medication. The inquest identified concerns including failure to diagnose obesity hypoventilation syndrome, inadequate consideration of promethazine, failure to recognise the seriousness of a life-threatening situation, and wider care, observation, record-keeping and hospital communication issues.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to document risk-benefit analysis for pertinent respiratory-affecting medication

    Wider context from the report

    “5. The section headed “Drug History” was not completed on the Discharge Form on Ben King’s attendances on 9 or 12 July 2020. On 10 July, it states “nil significant”. This is despite Ben King being prescribed Promethazine, a sedative medication, affecting the respiratory system. Evidence was heard that not all prescribed medications could be expected to be included in “the small space” provided. That this is a medication where consideration would have been given to a risk vs benefit analysis but there was no evidence of any such analysis. Regulation 28 evidence was that not all medication can be listed; only “pertinent” medication. ”

    Source location

    Ben Buster KING · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Highlight the potential adverse link between Promethazine and obesity hypoventilation syndrome through departmental clinical governance.

    Verbatim wording from the response

    “Obesity hypoventilation syndrome is a rare condition that the ED team had not come across before. An adverse link with Promethazine has been highlighted amongst the team through the departmental clinical governance process, to inform their assessment of future patients.”

    Source location

    2021-0250-Response-from-Norfolk-and-Norwich-University-Hospitals_Published
    Page 3 · response
    Published 23 July 2021

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Medication changes or recommendations were not specified because clinicians judged Promethazine unlikely to have caused the patient's decline or attendance.

    Verbatim wording from the response

    “Evidence was heard that not all prescribed medications could be expected to be included in “the small space” provided. That this is a medication where consideration would have been given to a risk vs benefit analysis but there was no evidence of any such analysis. Regulation 28 evidence was that not all medication can be listed; only “pertinent” medication. Promethazine would appear to be such a medication.”

    Source location

    2021-0250-Response-from-Norfolk-and-Norwich-University-Hospitals_Published
    Page 3 · response
    Published 23 July 2021

    Open published response
  4. Manchester South

    AI-generated summary

    Steven Terence Allen · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Steven Terence Allen was found unresponsive at home on 25 October 2020, and toxicology found a fatal level of prescribed medication; the medical cause of death was recorded as combined drug toxicity. Concerns included prescribing oxycodone and other medications despite a history of addiction, self-harm and poor use of substances, with telephone consultations during Covid-19 and additional replacement prescriptions sometimes issued with little challenge.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to account for addiction, self-harm and poor substance use when prescribing medication

    Wider context from the report

    “The inquest heard that he had a chaotic lifestyle and a history of drug addiction. He was in significant pain and was prescribed medication to manage his pain including oxycodone. He was prescribed this and additional medications although there was a history of addiction, self-harm and poor use of prescribed and illicit substances. Prescribing of these medications was done through telephone consultations due to Covid 19 and on occasion additional replacement prescriptions were given with little challenge. ”

    Source location

    Steven Terence Allen · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Continue discussions with Primary Care Network leads to explore Stockport Integrated Pharmacy Service support for optimising medication reviews.

    Verbatim wording from the response

    “• The Medicines Management Team is currently in discussion with the Primary Care Network (PCN) Leads to explore how the Stockport Integrated Pharmacy Service (SIPS) can support GP Practices in optimising medication reviews for this patient cohort.”

    Source location

    2021-0190-Response-from-Stockport-Clinical-Commissioning-Group-Redacted
    Page 2 · response
    Published 4 June 2021

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Remind Stockport GPs about available opioid-prescribing resources and how to seek support through the next pharmacy newsletter.

    Verbatim wording from the response

    “Greater Manchester Medicines Management Group (GMMMG) Opioid Prescribing for Chronic Pain: Resource Pack”

    Source location

    2021-0190-Response-from-Stockport-Clinical-Commissioning-Group-Redacted
    Page 2 · response
    Published 4 June 2021

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Existing prescribing guidance and clinician adherence are considered sufficient because the incident is regarded as isolated.

    Verbatim wording from the response

    “The Practice take on board the comments included within the Regulation 28 Report and have undertaken a review of this case and looked at their processes for the management of prescribing for patients in this vulnerable cohort. The practice are satisfied that this was an isolated case and that all clinicians do adhere to guidance in relation to informed prescribing and support of this patient group.”

    Source location

    2021-0190-Response-from-Stockport-Clinical-Commissioning-Group-Redacted
    Page 1 · response
    Published 4 June 2021

    Open published response
  5. Stoke-on-Trent and North Staffordshire

    AI-generated summary

    Michele Brenda Duckworth · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Michele Brenda Duckworth, who had paraplegia, end stage renal failure and a renal transplant requiring immunosuppression, was admitted with profuse diarrhoea and low blood pressure and later deteriorated with sepsis. She died on 23 February 2020, with the post-mortem finding death due to Escherichia coli bacteraemia of unknown source. The principal concern was that Tazocin was prescribed and continued despite previous ESBL colonisation, contrary to the trust guideline.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to identify and correct inappropriate antibiotic continuation during ward transfer and medical reviews

    Wider context from the report

    “(1) The deceased was incorrectly prescribed Tazocin when she was previously colonised with ESBL. It was initially prescribed when she was on the renal ward and was continued when she was transferred to the Intensive Care Department. The antibiotic given in that context was not the antibiotic suggested in the trust guideline, and it was missed after several medical reviews. ”

    Source location

    Michele Brenda Duckworth · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
  6. Manchester South

    AI-generated summary

    Wendy Margaret Wilkes · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Wendy Margaret Wilkes was found at her home on 6 August 2019, with toxicology showing a fatal level of ethanol and concomitant use of gabapentin, zopiclone, diazepam and amitriptyline. Concerns were raised about the absence of a clear system for alert notes and follow-up reviews, and about whether prescribers were aware of her high alcohol use and assessed the risks of mixing alcohol with her medication.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to assess the risk of mixing alcohol with prescribed medication

    Wider context from the report

    “The inquest heard that the GP practice did not appear to have a system to ensure that prescribers were aware that her alcohol use was high and to assess the risk of mixing alcohol with the prescribed medication. ”

    Source location

    Wendy Margaret Wilkes · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Flag patients at risk from neuropathic medication and alcohol dependence, conduct medication reviews, and contact them about medication and alcohol consumption.

    Verbatim wording from the response

    “Alert Note/Review System effective from 25 February 2020 The practice has identified relevant existing patients by running reports for patients coded on the practice’s clinical system as using neuropathic medication, cross referenced with patients coded with alcohol dependency who have had an intentional or accidental overdose. A “flag” is now placed on these patients’ medical records and a medication review is undertaken. The patients are then contacted to discuss their medication and their alcohol consumption.”

    Source location

    2020-0095-Response-from-Tameside-Glossop_Redacted
    Page 2 · response
    Published 18 May 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop and distribute guidance to practices on identifying and managing patients prescribed neuropathic drugs or opioids who may be alcohol-dependent.

    Verbatim wording from the response

    “Tameside and Glossop Clinical Commissioning Group (CCG) actions ████████, Director of Commissioning, is accountable to ensure that in line with the Coroner’s request, the following actions will be undertaken:”

    Source location

    2020-0095-Response-from-Tameside-Glossop_Redacted
    Page 2 · response
    Published 18 May 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Issue an alert to all GP practices about alert notes, follow-up reviews and considering systems to identify high alcohol use during prescribing.

    Verbatim wording from the response

    “3. An alert will be issued to all GP practices to ensure that they have clear systems of alert notes/follow up review appointments for individuals with extensive prescribed medications. The alert also requests GP practices consider how their systems can alert prescribers to patients with high alcohol usage when prescribing medications to ensure effective risk assessments can be carried out.”

    Source location

    2020-0095-Response-from-Greater-Manchester-Health-and-Social-Care-Partnership
    Page 2 · response
    Published 18 May 2020

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    The named Clinical Commissioning Group is responsible for addressing the concerns raised about GP practice alert systems and prescribing risk assessment.

    Verbatim wording from the response

    “I have noted that your Regulation 28 letter has also been sent to the Clinical Commissioning Group concerned and I will leave it to the named respondent to address the concerns which you have addressed. My letter therefore addresses the issues that fall within the remit of GMHSCP.”

    Source location

    2020-0095-Response-from-Greater-Manchester-Health-and-Social-Care-Partnership
    Page 2 · response
    Published 18 May 2020

    Open published response
  7. West Sussex

    AI-generated summary

    Katharine Eva Stamp · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Katharine Eva Stamp died while detained under the Mental Health Act from sudden cardiac arrhythmia due to hypoxia, with the hypoxia described as involving aspiration pneumonia, probable sleep apnoea, obesity, smoking and clozapine effects. The report raised concerns that clozapine side effects, particularly in relation to smoking and pneumonia, were under-appreciated and that the BNF did not provide sufficient clarity to prescribers; it also stated that the lack of an effective national weight-gain monitoring programme for mental health inpatients was causally linked to her obesity and probable sleep apnoea.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Under-appreciation of clozapine side effects relating to smoking and pneumonia

    Wider context from the report

    “The side effects of clozapine, with specific reference to smoking and pneumonia, are under-appreciated Professor ████████ gave expert evidence to the Court These side effects may be rare, but they are still important The BNF does not provide sufficient clarity to prescribers about these side-effects ”

    Source location

    Katharine Eva Stamp · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report
  8. Manchester South

    AI-generated summary

    Graham Earl · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Graham Earl had pulmonary fibrosis diagnosed while receiving Amiodarone therapy and was not referred back to the cardiologist. He later developed influenza, deteriorated, and died at Stepping Hill Hospital on 16 February 2019. The principal concerns were that the link between Amiodarone and pulmonary fibrosis was not recognised promptly, the medication was amended without reference to secondary care, and there was insufficient awareness of escalation procedures for side effects.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    CCG classification of the drug as green despite known side effects

    Wider context from the report

    “4. The drug is currently green on the CCG classification. In other CCG areas it is amber given the known side effects. ”

    Source location

    Graham Earl · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
  9. South Wales Central

    AI-generated summary

    Mr. Christopher Summerhayes · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Mr. Christopher Summerhayes was found deceased at his home address after a significant medical history including double scoliosis, treatment-resistant schizophrenia and a complex regime of around 12 daily medications. The concerns included the prescription of clozapine alongside other medications, substantial weight gain and possible effects on his cardiovascular system, as well as a possible familial lipid disorder. The inquest concluded that the medical cause of death was ischaemic heart disease, with a narrative determination referring to atypical early-onset coronary artery atherosclerosis and complex prescribed medications.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Potential contraindication to clozapine from familial lipid disorder

    Wider context from the report

    “(1) In relation to Christopher Summerhayes, Clozapine was prescribed as a concomitant medication alongside approximately 11 other drugs including another anti-psychotic medication. Either alone or interaction with other prescribed medication, a large increase in weight occurred to >101kg (BMI 33.1) (reported side effect of clozapine) which had a ‘knock-on’ effect for his cholesterol and lipid levels and cardiovascular system. The usual dose is 200-450mg daily with the maximum dose being 900mg (BNF) which does not consider concomitant medications. Signs of prescription overdose include collapse and hallucinations which could be mistaken for unresolved symptoms of schizophrenia i.e. lack of drug efficacy encouraging dose increase. Blood levels of clozapine may rise in response to smoking cessation which Mr. Summerhayes had advised we was commencing. (2) He may have suffered from a familial lipid disorder (present in other family members) which had it been confirmed would likely to have contraindicated Clozapine. ”

    Source location

    Mr. Christopher Summerhayes · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to distinguish clozapine overdose signs from unresolved schizophrenia symptoms

    Wider context from the report

    “(1) In relation to Christopher Summerhayes, Clozapine was prescribed as a concomitant medication alongside approximately 11 other drugs including another anti-psychotic medication. Either alone or interaction with other prescribed medication, a large increase in weight occurred to >101kg (BMI 33.1) (reported side effect of clozapine) which had a ‘knock-on’ effect for his cholesterol and lipid levels and cardiovascular system. The usual dose is 200-450mg daily with the maximum dose being 900mg (BNF) which does not consider concomitant medications. Signs of prescription overdose include collapse and hallucinations which could be mistaken for unresolved symptoms of schizophrenia i.e. lack of drug efficacy encouraging dose increase. Blood levels of clozapine may rise in response to smoking cessation which Mr. Summerhayes had advised we was commencing. (2) He may have suffered from a familial lipid disorder (present in other family members) which had it been confirmed would likely to have contraindicated Clozapine. ”

    Source location

    Mr. Christopher Summerhayes · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Apply NICE-aligned physical-health monitoring arrangements for patients taking Clozapine.

    Verbatim wording from the response

    “Guidance from the National Institute of Health and Care Excellence (NICE) for assessing physical health of patients on Clozapine is available on their website (www.nice.org.uk) and monitoring arrangements are in place in line with this guidance.”

    Source location

    2019-0263-Response-by-University-Health-Board
    Page 2 · response
    Published 17 October 2019

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Existing medicines reconciliation, pharmacist support, NICE monitoring and promoted polypharmacy reviews address medication interaction and prescribing risks.

    Verbatim wording from the response

    “The UHB has a Medicines Code in place and this was updated in 2018. It contains a section on medicines reconciliation. It sets out the responsibilities of various healthcare professionals in this process, including doctors, the pharmacy team and other prescribers.”

    Source location

    2019-0263-Response-by-University-Health-Board
    Page 2 · response
    Published 17 October 2019

    Open published response
  10. Manchester South

    AI-generated summary

    Hannah Dolly Kaur Bharaj · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Hannah Dolly Kaur Bharaj had anorexia, depression and fluctuating suicidal ideation, and died at Salford Royal Hospital on 13 July 2018 from injuries sustained after jumping from a first-floor café. Concerns included inadequate communication and discharge planning, unsuitable placement and care coordination, incomplete sharing of clinical information, and the safety of the café balustrade and adjacent table.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to consider discharge medication and prescribing risk

    Wider context from the report

    “2. There was no clear evidence of consideration of discharge medication and risk around prescribing of medication post discharge from the EDU. As a result Hannah was prescribed a month’s supply of medication; ”

    Source location

    Hannah Dolly Kaur Bharaj · Prevention of Future Deaths report
    Page 3 · concerns

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Data last updated 7 September 2026