Recurring concern

Unsafe anticoagulant management

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First reported 5 Sep 2013•Latest report 28 May 2026

Definition

What this concern includes

Includes failures of controls specifically dedicated to anticoagulant management, including prescribing clarity and reconciliation, anticoagulation-chart accuracy, INR or other required monitoring, senior clinical review, risk-sensitive guidance, escalation and consideration of anticoagulant treatment in relevant clinical circumstances.

Not included

  • Excludes generic medication-prescribing, record-keeping, staffing, training or communication deficiencies unless they are specifically tied to anticoagulant management.
  • Excludes general bleeding-risk controls for patients taking antithrombotic medication when the assertion does not concern anticoagulant management itself.
  • Excludes medication administration, supply or continuity failures where anticoagulant treatment management is not the identified unsafe condition.
  • Excludes unrelated thromboprophylaxis, venous-thromboembolism prevention and non-anticoagulant medication concerns.
Reports
25

Distinct published reports

Individual concerns
34

A report can raise multiple concerns

Date range
2013–2026

First to latest report issue date

Stated actions
28

Described in published responses

Reports over time

Reports over time

Reports about this concern issued each year.

* 2026 is projected from reports observed to 7 Sep 2026.

Most frequent recipients

Most frequent recipients

Reports about this concern sent to each recipient.

National Institute for Health and Care Excellence5
NHS England4
Cwm Taf Morgannwg University Local Health Board3
Department of Health and Social Care3
Recipient name withheld3
Senedd Cymru3
Welsh Government3
Aneurin Bevan University LHB1
Barking, Havering and Redbridge University Hospitals NHS Trust1
Barnsley Hospital NHS Foundation Trust1
Birmingham Women'S and Children'S NHS Foundation Trust1
British Cardiovascular Society1
Care Quality Commission1
East Kent Hospitals University NHS Foundation Trust1
Frimley Health NHS Foundation Trust1

Concerns and responses across reports

Only concerns grouped under this recurring concern are included. Select any concern, action or position to view the source wording.

  1. Essex

    AI-generated summary

    Lacey Carole Anne HEATH · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Lacey Carole Anne HEATH died on 16 February 2025 after collapsing at home and suffering cardiac arrest en route to hospital. The death followed thrombosis and complete stenosis of her mechanical aortic valve in the context of sub-therapeutic anticoagulation. Concerns included difficulty maintaining therapeutic anticoagulation, lack of access to affordable at-home monitoring, absence of a funding application, insufficient medical review or haematology referral, and inadequate clinical records.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of General Practitioner funding for at-home anticoagulation testing supplies

    Wider context from the report

    “4. Ms Heath could not afford to fund the at home monitor as this was financially prohibitive for her being on a low income. The monitor was expensive and there is no obligation for General Practitioners to fund the testing strips and incidentals required to facilitate testing. As this would be a lifelong commitment for a woman who was only 34 years-old, Ms Heath was not able to take the advice of her expert clinical team and was compelled to have alternative prescribing that was not successful in keeping her INR within therapeutic range. ”

    Source location

    Lacey Carole Anne HEATH · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Use of alternative anticoagulation medication associated with high INR readings and bleeding risk

    Wider context from the report

    “2. Due to the complexity of her case, Ms Heath’s anticoagulation was under the care of the acute hospital team. Alternative anticoagulation medication had resulted in high INR readings and significant risks associated with bleeding. ”

    Source location

    Lacey Carole Anne HEATH · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Establish an escalation process for clinically required anticoagulation monitoring equipment or consumables when financial barriers arise, including funding guidance, staff communication and application audits.

    Verbatim wording from the response

    “By the end of September 2026 we will have a process for escalating cases where recommended anticoagulation monitoring equipment or consumables may be clinically required but financial barriers are identified. This will include signposting to available funding routes, individual funding consideration, charitable support or commissioner discussion where applicable.”

    Source location

    Response from Mid & South Essex NHS Foundation Trust
    Page 3 · response
    Published 6 August 2026

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Introduce documented senior-clinician and, where appropriate, haematology review requirements, an updated operating procedure, staff communication and governance audits for complex anticoagulation cases.

    Verbatim wording from the response

    “We plan to introduce a documented requirement for complex cases including high INR readings, bleeding risk, recurrent instability or failed alternative regimes to be reviewed by a senior clinician and, where appropriate, haematology. This will establish a clear escalation route for complex anticoagulation patients.”

    Source location

    Response from Mid & South Essex NHS Foundation Trust
    Page 2 · response
    Published 6 August 2026

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Commissioning responsibility for at-home INR monitoring rests with Integrated Care Boards, varying according to the clinical pathway and service specification.

    Verbatim wording from the response

    “Funding responsibility for at-home INR monitoring, can sit across different parts of the system depending on the clinical pathway and who held responsibility for ongoing anticoagulation management. From an anticoagulation perspective, commissioning of services is the responsibility of Integrated Care Boards (ICBs).”

    Source location

    Response from NHS England
    Page 2 · response
    Published 6 August 2026

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Long-term additional injections were not clinically appropriate after alternative anticoagulation regimens had been trialled.

    Verbatim wording from the response

    “1. Ms Heath was noted to be warfarin resistant and alternative medication regimes were not successful in keeping Ms Heath within a therapeutic range for her required lifelong requirement to have anticoagulation to prevent a significant risk of death. The GP and hospital clinicians trialled different combinations of appropriate therapy which included additional injections when required. This was not considered to be clinically appropriate long-term.”

    Source location

    Response from Mid & South Essex NHS Foundation Trust
    Page 1 · response
    Published 6 August 2026

    Open published response
  2. Berkshire

    AI-generated summary

    John Albert TARRANT · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    John Albert Tarrant, aged 84, died at Wexham Park Hospital after an unwitnessed fall while an inpatient on 29 April 2025, sustaining a brain bleed that later became unsurvivable. The principal concerns were inaccurate falls risk assessments and insufficient awareness or prompting regarding the urgency of anticoagulation reversal after a fall.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure of the post-falls proforma to prompt consideration of anticoagulation reversal and urgency

    Wider context from the report

    “2. Anti coagulation risk awareness The doctor who reviewed the CT results and neurosurgery advice after Mr Tarrant fell did not appreciate the urgency of the situation. I found in this inquest that due to timing issues this was not likely to have affected the outcome for Mr Tarrant. I heard from the consultant witness that the risks of anticoagulation are poorly understood. The post falls proforma was reviewed in court and, whilst it asked whether the patient was on anticoagulation medication, it did not provide a prompt about this during the post fall medical planning section. This led to a concern that the importance of considering and administering an anticoagulation reversal medication and the urgency of such a need may be underappreciated. ”

    Source location

    John Albert TARRANT · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
  3. Nottinghamshire

    AI-generated summary

    Ruth Diane Eggleton · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Ruth Diane Eggleton fell in her garden on 2 April 2023 and sustained a head injury with a small subdural haemorrhage. She was taking Rivaroxaban, which was not withheld or reversed, and she was discharged from hospital; the report identified concerns about the lack of an evidence-based protocol for managing DOAC anticoagulation.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of an evidence-based protocol for withholding or reversing DOAC and prescribing alternative anticoagulant medication

    Wider context from the report

    “1. There is a lack of evidence-based protocol for determining when to withhold and/or reverse DOAC, and when to prescribe alternative anticoagulant medication. I heard evidence from clinicians that the lack of such a protocol has led to divergence of practice amongst clinicians. I am not reassured that necessary actions to address the serious issue identified are in place. ”

    Source location

    Ruth Diane Eggleton · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Continue monitoring new evidence on DOAC anticoagulation decisions.

    Verbatim wording from the response

    “NICE will continue to monitor new evidence in this area of practice, and will develop or update our guidance accordingly.”

    Source location

    Response from NICE
    Page 2 · response
    Published 4 July 2024

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Develop or update NICE guidance on DOAC anticoagulation decisions in response to new evidence.

    Verbatim wording from the response

    “NICE will continue to monitor new evidence in this area of practice, and will develop or update our guidance accordingly.”

    Source location

    Response from NICE
    Page 2 · response
    Published 4 July 2024

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    NICE cannot develop useful guidance on DOAC reversal decisions because high-quality evidence is lacking and decisions require individual clinical judgement.

    Verbatim wording from the response

    “We agree that consideration should be given to reversing and withholding anticoagulation when a person prescribed these medications experiences significant bleeding. The reason for anticoagulation (which is not mentioned in your report) must be balanced against the estimated risk of further bleeding. In rare cases, alternative anticoagulation may be considered. Unfortunately, there is very little research evidence on which guidelines relevant to this complex decision could be based, and a high degree of clinical judgement is required in each case.”

    Source location

    Response from NICE
    Page 1 · response
    Published 4 July 2024

    Open published response
  4. Leicester City and South Leicestershire

    AI-generated summary

    John Kenneth PARRY · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    John Parry, aged 72, was admitted to Leicester Royal Infirmary on 4 July 2023 after feeling unwell and later suffered two unwitnessed falls. He died on 7 July 2023 after a spontaneous intracerebral bleed was diagnosed. The inquest raised concerns that neurological observations after the falls were not carried out in accordance with hospital policy, the calculations were inaccurate, and a CT head scan that should have occurred within one hour was not performed. A separate concern concerned communication and information-sharing when prescribing warfarin.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to communicate all relevant patient information to doctors dosing warfarin

    Wider context from the report

    “The evidence heard raised a concern about the safe prescribing of warfarin. When a doctor is asked by a nurse to dose the warfarin, the accepted practice is that the doctor relies on the nurse to give all relevant information and the doctor only checks the INR blood results from the laboratory. There is no requirement or expectation that the doctor looks at the patient’s medical records or seeks information about the patient. At the inquest evidence was heard that the nurse had not communicated all relevant information. Although in this case it did not have an adverse outcome, it was accepted that there was a risk that if a doctor does not have all relevant information, warfarin could be prescribed and administered and there could be a risk of death. Evidence was given that this lack of appropriate communication was believed to be unusual but it was accepted that it is not necessarily known how unusual because it would probably only become apparent in cases of an adverse outcome. ”

    Source location

    John Kenneth PARRY · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Re-emphasised clear anticoagulation communication, shared case learning with clinical leaders and forums, and delivered repeated daily-brief reminders to clinical teams.

    Verbatim wording from the response

    “Following on from the issues raised in your Regulation 28 Report we have re-emphasised the importance of clear and effective communication between all colleagues in particular regarding anticoagulation. This includes sharing learning from this case with all ward leaders, matrons and through our chief nurse forums. A reminder to all clinical teams via the daily brief of the importance of giving clear information was included in the week commencing 29/07/24 and was repeated in the week commencing 05/08/24. The daily brief has three key messages and is read out to all clinical teams at every huddle every day for a week.”

    Source location

    Response from University Hospitals Leicester
    Page 1 · response
    Published 28 June 2024

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Embed a digital reminder requiring MDT colleagues to record pertinent clinical information and patient-condition changes in digital warfarin dosage requests.

    Verbatim wording from the response

    “To help improve communication further, we will embed a digital reminder for all MDT colleagues to include pertinent clinical information or any changes to the patient’s condition when generating a digital warfarin dosage request for the patient. Due to a need to ensure appropriate testing and governance, these changes will take time to fully implement across the whole of UHL, but we anticipate this will occur by December 2025. Our eHospital team, which is chaired by our Medical Director will oversee these changes.”

    Source location

    Response from University Hospitals Leicester
    Page 1 · response
    Published 28 June 2024

    Open published response
  5. Warwickshire

    AI-generated summary

    David RILEY · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    David Riley developed a pericardial effusion after atrial fibrillation ablation and later suffered a stroke before dying on 10 June 2023. Concerns included inconsistent decisions about pausing Apixaban, delays in restarting it, inadequate communication and continuity of care, and difficulties using computerised clinical records.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to coordinate pericardiocentesis timing with the duration of DOAC interruption

    Wider context from the report

    “2. Effective communication From the evidence, there was a failure to effectively communicate, recognise and act on directions that were time critical, such as restarting the DOAC as directed. It does not appear that there was any consideration as to the timing of the pericardiocentesis to ensure that the DOAC was paused for a short a time as possible. The evidence suggested that this may be due to lack of continuity of care and the difficulties in the way in which computerised clinical/pharmacy records are updated and accessed. Clear communication between medical staff is essential to patient care. ”

    Source location

    David RILEY · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Operational responsibility for delivering health services and responding to related concerns lies with NHS England.

    Verbatim wording from the response

    “NHS England is operationally responsible for delivering health services across the country and will be responding directly to your concerns at length. NHS England is an executive non-departmental public body, sponsored by the Department of Health and Social Care.”

    Source location

    Response from DHSC
    Page 2 · response
    Published 8 August 2024

    Open published response
  6. Surrey

    AI-generated summary

    Jeffrey MARSHALL · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Jeffrey Marshall died at St Peter’s Hospital in Chertsey on 13 December 2023 after suffering an ischaemic stroke caused by thrombosis of the basilar artery, following a fall and subdural haematoma. His anticoagulation had been withheld for 47 days. The principal concern was the lack of national guidance on when to recommence anticoagulation after a head injury and the lack of guidance on discussing the risks and benefits of withholding it with patients.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to provide recommendations for discussing anticoagulation withholding risks and benefits with patients

    Wider context from the report

    “- Mr Marshall was prescribed anticoagulation (Edoxaban) to mitigate his increased risk of developing thrombus due to atrial fibrillation and a permanent pacemaker; - Anticoagulation was withheld following a traumatic head injury, in accordance with NICE guidance; - There is no national guidance to assist clinicians in determining when anticoagulation should be recommenced in this scenario, nor any recommendation for clinicians to discuss the risks and benefits of withholding anticoagulation with patients to enable them to make an informed decision as to when to recommence anticoagulation. Consideration should be given to whether any steps can be taken to address the above concerns. ”

    Source location

    Jeffrey MARSHALL · Prevention of Future Deaths report
    Page 3 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Assess the issue through the guidelines surveillance process to determine whether guidance recommendations should be updated or newly issued.

    Verbatim wording from the response

    “In summary, we agree that this specific question is not well covered by current guidance. NICE will consider the issues raised through our guidelines surveillance team and process, and update or issue new guidance recommendations, accordingly, depending on the outcome of these considerations. We will also discuss with relevant specialist societies the possibility of reaching a consensus statement on this subject.”

    Source location

    Response from NICE
    Page 2 · response
    Published 14 August 2024

    Open published response
  7. North East Kent

    AI-generated summary

    KEITH RUPERT DIMOND · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Keith Dimond died on 24 November 2021 at Queen Elizabeth Queen Mother Hospital following a catastrophic bleed from a ruptured iliac artery aneurysm, with anticoagulation contributing to the excessive bleeding. Concerns included communication failures about the known iliac artery aneurysm, lack of information about bleeding risks when anticoagulation was prescribed, delayed escalation when he deteriorated, and haematology advice on anticoagulation not being followed on two occasions.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Failure to record reasons for not following Consultant Haematologist anticoagulation advice

    Wider context from the report

    “(3) Anti-coagulation on readmission was considered complex and the advice of a Consultant Haematologist was sought but not followed on two occasions: (a) Beriplex and Vitamin K was administered. There was no rationale noted as to why advice to withhold Beriplex was not followed. (b) There was no record as to why advice to give prophylactic clexane was not administered. ”

    Source location

    KEITH RUPERT DIMOND · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Communicate to clinical teams the requirement to document decision-makers and rationales when withholding haematology-advised anticoagulant treatment.

    Verbatim wording from the response

    “It is good practice for all clinical teams to seek advice from the haematologist regarding anti-coagulants if considered complex. Since this incident, we have communicated the importance of documenting who made the decision and the rationale behind withholding treatment that has been advised by the haematologist, for example in response to a rapidly changing clinical picture or additional information coming to light, to all clinical teams. This has been through via training and written communications from the clinical director. This element will also be included within the team learning review at the morbidity and mortality meetings for shared learning.”

    Source location

    Response from East Kent Hospitals University
    Page 2 · response
    Published 28 October 2022

    Open published response
  8. Essex

    AI-generated summary

    Ann Margaret Smith · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Ann Margaret Smith was admitted to Princess Alexandra Hospital, suffered an unwitnessed fall the following day, sustained a head injury and died four days later. The principal concern was uncertainty about managing anticoagulation after the fall, including the lack of a local protocol for patients over 65 on anticoagulants who sustain head trauma.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of a local protocol for managing anticoagulated patients over 65 receiving treatment-dose clexane who sustain head trauma

    Wider context from the report

    “1. There was uncertainty as to how to deal with the anti-coagulation aspect of the deceased’s care in the wake of the fall. There is the lack of a local protocol (part of the Falls Policy) for the management of the sub-group of patients over 65 on anticoagulants and being given treatment dose of clexane for another clinical reason eg suspected pulmonary embolus, who sustain head trauma. ”

    Source location

    Ann Margaret Smith · Prevention of Future Deaths report
    Page 1 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Establish a multidisciplinary task and finish group to review and improve anticoagulation and falls protocols.

    Verbatim wording from the response

    “Goal: 1. To establish a task and finish group to review the current protocols and make necessary changes”

    Source location

    Response from The Princess Alexandra Hospital NHS Trust 2
    Page 3 · response
    Published 21 December 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Update, approve and distribute falls policies and post-fall guides covering anticoagulation decisions, observation requirements and documented action plans.

    Verbatim wording from the response

    “Goal: 2. To review the current falls prevention policy and to provide an update to include the management of this sub group of patients. This will include the quick reference guides on post falls management that are included in the appendices of the policy”

    Source location

    Response from The Princess Alexandra Hospital NHS Trust 2
    Page 4 · response
    Published 21 December 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Amend Nerve Centre to require completion of every section of neurological observations and communicate the change to ward leaders.

    Verbatim wording from the response

    “4b. For an update to be made to Nerve Centre to ensure that completion of all parts of neurological observations are mandatory”

    Source location

    Response from The Princess Alexandra Hospital NHS Trust 2
    Page 6 · response
    Published 21 December 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Make falls prevention and management training mandatory for clinical staff and incorporate the updated anticoagulation and neurological observation requirements.

    Verbatim wording from the response

    “5. For all of the above actions to be included in mandatory falls prevention and management training for all clinical staff”

    Source location

    Response from The Princess Alexandra Hospital NHS Trust 2
    Page 7 · response
    Published 21 December 2020

    Open published response
  9. Nottinghamshire

    AI-generated summary

    Marian DAY · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Marian Day died at Kings Mill Hospital on 18 November 2019 after a sudden collapse caused by a massive intra-abdominal haemorrhage. Warfarin was continued and administered despite suspected bleeding and an earlier plan to withhold it; the inquest found that this prescription error made a contribution to the haemorrhage. The report raises concerns about muddled prescribing systems, insufficient senior review, and unclear anticoagulant management plans.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Multiple charts and documents permitting muddled or omitted anticoagulant prescribing

    Wider context from the report

    “Whilst there has been a detailed Serious Incident review of the circumstances of Mrs Day’s death conducted by the Trust, it remains unclear as to how and why these prescription errors occurred. It is my view that a similar prescription error could occur again, as there remains a number of different charts and documents that allow for muddled prescribing of, or omission of, anticoagulants, when there are complex medical conditions and concern re likely bleeding. Whilst the development of an electronic prescribing system may increase the probability of more clarity in prescription of anticoagulants, this is not in place currently. In addition, this alone in my view will not ensure oversight of anticoagulant management, unless other measures are taken to ensure senior review of patients, and a clear prescription plan recorded for all staff to follow. ”

    Source location

    Marian DAY · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of senior review of patients for anticoagulant management

    Wider context from the report

    “Whilst there has been a detailed Serious Incident review of the circumstances of Mrs Day’s death conducted by the Trust, it remains unclear as to how and why these prescription errors occurred. It is my view that a similar prescription error could occur again, as there remains a number of different charts and documents that allow for muddled prescribing of, or omission of, anticoagulants, when there are complex medical conditions and concern re likely bleeding. Whilst the development of an electronic prescribing system may increase the probability of more clarity in prescription of anticoagulants, this is not in place currently. In addition, this alone in my view will not ensure oversight of anticoagulant management, unless other measures are taken to ensure senior review of patients, and a clear prescription plan recorded for all staff to follow. ”

    Source location

    Marian DAY · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Complete a multidisciplinary review of the warfarin prescribing, dosing and supporting-documentation process.

    Verbatim wording from the response

    “I am responding to your Regulation 28 Report to Prevent Future Deaths, issued following the inquest touching the death of Mrs Marian Day. You raised concern about prescription errors that led to Mrs Day receiving two doses of warfarin on consecutive days despite there being a medical plan that it should be withheld. You were concerned that a similar error may occur again in part due to the number of charts involved in the prescribing and dosing of warfarin. In order to address your concerns we have undertaken a multidisciplinary (MDT) review of our warfarin process, prescription and supporting documentation to address these concerns.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 1 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Document decisions to change existing warfarin plans on the yellow dosing chart and in the clinical record when made.

    Verbatim wording from the response

    “1. Decisions on changes to existing warfarin plans to be documented on the yellow dosing chart at the time they are made, as well as in the clinical record. This will ensure that all doctors dosing warfarin are aware of the current plan even if they are not part of the treating team.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 3 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Require senior-doctor discussion and full documentation before changing an existing warfarin plan.

    Verbatim wording from the response

    “2. Changes to existing warfarin plans to be made only following discussion with senior doctors, and fully documented.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 3 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Explore electronic Nervecentre alerts to inform ward doctors when INR results become available.

    Verbatim wording from the response

    “Advancement of laboratory technology including electronic results makes most results available earlier in the day. Dosing before the parent team finish their shift is ideal as they will know their patients’ needs. To achieve this we are working towards:”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 4 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Consider adding prompts to warfarin documentation addressing thrombosis and bleeding risks during prescribing decisions.

    Verbatim wording from the response

    “4. Consideration of the benefits of prompts in the warfarin documentation with regard to the risks for thrombosis versus the risks of bleeding to aide prescribing decision making. For discussion at Medicine Safety Group December 2020 [Assistant Chief Pharmacist and Medication Safety Officer to Present]”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 4 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Disseminate guidance reminding staff to amend both charts when withholding warfarin doses.

    Verbatim wording from the response

    “5. Further Education and Awareness:”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 4 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Include the patient story in junior-doctor training on warfarin prescribing errors.

    Verbatim wording from the response

    “• Add this patient story into training for juniors to highlight the potential outcome of warfarin prescribing errors: Training updated November 2020 for inclusion in August 2021 junior doctor induction and going forwards.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 4 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent action was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Audit compliance with documentation requirements for the immediate warfarin safety actions.

    Verbatim wording from the response

    “6. Pharmacy to audit documentation compliance for the immediate further actions described above. December 2020 Assistant Chief Pharmacist and Medication Safety Officer to Conduct”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 4 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    The expert panel concluded that changing the entire warfarin prescription process would be unlikely to prevent future deaths and could increase prescribing errors.

    Verbatim wording from the response

    “changing the entire process by altering the prescription charts. The differing expertise outlined that if this was conducted then there would be an increased likelihood in prescribing and dosing errors affecting patients. Therefore it was concluded by this expert panel that this would be highly unlikely not to help prevent future deaths. In addition the roll out of EPMA (electronic prescribing) at SFHFT, which includes warfarin prescribing, is expected to pilot in February 2021 and realistically any changes to paper documentation would be highly unlikely to complete Trust governance processes and printing before this time.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 5 · response
    Published 30 November 2020

    Open published response

    Source evidence

    How this respondent position was interpreted

    PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

    PFD Monitor interpretation

    Paper documentation changes could not realistically complete governance and printing processes before electronic prescribing was piloted.

    Verbatim wording from the response

    “changing the entire process by altering the prescription charts. The differing expertise outlined that if this was conducted then there would be an increased likelihood in prescribing and dosing errors affecting patients. Therefore it was concluded by this expert panel that this would be highly unlikely not to help prevent future deaths. In addition the roll out of EPMA (electronic prescribing) at SFHFT, which includes warfarin prescribing, is expected to pilot in February 2021 and realistically any changes to paper documentation would be highly unlikely to complete Trust governance processes and printing before this time.”

    Source location

    2020-0199-Response-from-Kings-Mill-Hospital-Redacted.pdf
    Page 5 · response
    Published 30 November 2020

    Open published response
  10. Manchester South

    AI-generated summary

    Maureen Waterfall · Prevention of Future Deaths report

    This summary was generated using AI from the published report. Please read the original report for the complete account.

    Report summary

    Maureen Waterfall fell at home on 12 July 2019 while taking the anticoagulant Edoxaban and sustained a head injury that led to a subdural haematoma. She died at Willow Wood Hospice on 26 July 2019. Concerns included the lack of a licensed specific antidote for Edoxaban, uncertainty about treatment effectiveness and timing, the absence of national guidance, and the storage of antidote supplies away from the resuscitation unit.

    Read the report on judiciary.uk

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of a national protocol for timely anticoagulant antidote administration

    Wider context from the report

    “2. The inquest was told that head injury patients who are prescribed Exodaban are at greater risk of continued bleeding to the brain than other patients as the absence of a specific antidote makes the reversal of the anticoagulant medication less certain. As with other newer anticoagulant drugs, there is little ability to monitor the effectiveness of the antidote. It was unclear if that understanding had been shared widely amongst non-tertiary centres to assist them in managing such patients. The inquest was told that, at SRFT which is a tertiary centre for neuro surgery/ neurology they have taken steps to set a target for the use of anticoagulant antidote drugs at 90 minutes from presentation. It was unclear if this target was feeding into development of a national protocol. It was unclear how in the absence of national guidance that information was being shared with DGHs which rely on tertiary centres for expertise. At TGH there was no clear target time for the administration of anti-coagulations. ”

    Source location

    Maureen Waterfall · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report

    Source evidence

    How this individual concern was interpreted

    PFD Monitor created a concise, searchable interpretation from the report wording shown below.

    PFD Monitor interpretation

    Lack of a clear target time for anticoagulant antidote administration

    Wider context from the report

    “2. The inquest was told that head injury patients who are prescribed Exodaban are at greater risk of continued bleeding to the brain than other patients as the absence of a specific antidote makes the reversal of the anticoagulant medication less certain. As with other newer anticoagulant drugs, there is little ability to monitor the effectiveness of the antidote. It was unclear if that understanding had been shared widely amongst non-tertiary centres to assist them in managing such patients. The inquest was told that, at SRFT which is a tertiary centre for neuro surgery/ neurology they have taken steps to set a target for the use of anticoagulant antidote drugs at 90 minutes from presentation. It was unclear if this target was feeding into development of a national protocol. It was unclear how in the absence of national guidance that information was being shared with DGHs which rely on tertiary centres for expertise. At TGH there was no clear target time for the administration of anti-coagulations. ”

    Source location

    Maureen Waterfall · Prevention of Future Deaths report
    Page 2 · concerns

    Open source report
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Data last updated 7 September 2026