Investigation and inquest
On 14th December 2017 I commenced an investigation into the death of Karl James Willis, DOB 19 May 1986. The investigation concluded at the end of the inquest on 17 August 2018. The conclusion of the inquest was
Medical cause of death –
1a Aspiration Pneumonitis
1b Amitriptyline and morphine toxicity
Conclusion - Misadventure
Circumstances of the death
Karl had been taking substantial amounts of prescribed medication and was under regular review and twice weekly medication collection with an intention to prevent excessive intake/overdose and to gradually reduce his dependency. A short time before his death, the GP had removed amitriptyline from his prescribed medications and replaced this with another drug, explaining the two should not be taken together.
Karl completed an online questionnaire with UK meds and was untruthful in most aspects of the information he disclosed, in order to secure a further online prescription of amitriptyline. He also refused permission for his GP to be advised of this prescription request.
Karl was found deceased at home and the toxicology confirmed the concentration of amitriptyline in the blood specimen is well above that seen after therapeutic dosage and within the reported fatal range. The concentration of morphine is sufficient to have significantly increased toxicity due to the amitriptyline.
Coroner’s concerns
(1) Amitriptyline is well recognised to have toxic effects when taken in excessive amounts or in conjunction with other medication
(2) Permitting the patient to “self certify” without any checks he can appropriately access this medication can allow the patient to give inaccurate answers, and therefore the questionnaire is open to deliberate abuse by those most vulnerable who have addiction problems
(3) Permitting the patient the option of not having the GP informed removes an otherwise effective safeguard. The GP had worked with extreme care and supported the patient over many months to try and reduce his excessive reliance on polypharmacy.