Investigation and inquest
On 7th October 2020 I commenced an investigation into the death of LESLEY MAWBY then aged 73 years. The investigation concluded at the end of the inquest on 21st May 2021. The narrative conclusion of the inquest was as follows:
Lesley Mawby died as a consequence of a recognised complication of chemotherapy treatment on a background of frailty due to malnutrition where there was a delay in commencing TPN Feeding.
The medical cause of death being
1a Multi-Organ Failure
1b Chemotherapy-Induced Bowel Toxicity
1c Multiple Myeloma
II Upper Gastrointestinal Haemorrhage, Gastritis, Sepsis
Circumstances of the death
Lesley Mawby suffered from myeloma. She was diagnosed with asymptomatic myeloma at the end of 2018. She remained symptom free until around April 2020 when she started experiencing back pain. Following an MRI scan in July 2020 the decision was made to start treating her Myeloma. She was treated with Lenalidomide and Dexamethasone and began her first cycle of treatment in August 2020. On 19th August 2020 she began to experience violent diarrhoea and vomiting and was admitted to Stepping Hill Hospital for treatment. The vomiting and diarrhoea continued due to drug induced bowel toxicity. She was unable to eat any food and her electrolytes became deranged. She was referred to the dietetics department, but the assessment was delayed by a miscalculation of the MUST Score and there were further delays in assessment by the dieticians due to staffing levels. She was reviewed by a dietician on 1st September 2020 and nasogastric feeding was started along with peripheral TPN on 2nd September 2020. Full TPN was started on 4th September 2020. Lesley had lost a significant amount of weight by this stage. Lesley had an atypical response to TPN and it was not possible to bring Lesley’s electrolytes and nutrition under control despite TPN and electrolyte replacement. In addition, she suffered from sepsis, upper gastrointestinal haemorrhage and she continued to deteriorate. She died on 5th October 2020 at Stepping Hill Hospital, Popular Grove, Hazel Grove Stockport of multi organ failure as a result of chemotherapy induced bowel toxicity which was caused by necessary treatment for multiple myeloma.
Coroner’s concerns
(1) It is a matter of concern that there are residual staffing shortages in the dietetic team leading to delays in assessments on weekdays and meaning weekend cover cannot be provided.