PFD report

Saif Mubeen Hussain · Prevention of Future Deaths report

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Issued 25 Nov 2021•Berkshire

Report record

Published report and response evidence

This page connects the concerns raised in this report with statements found in recipients’ published responses. A link shows a clear evidence connection; it does not assign responsibility.

View original report
Concerns
5

Raised in this report

Recipients
2

Named on the report

Responses found
1

Of 2 recipients

Stated actions
10

Described in responses

Source document

Full report text

This is the full text from the original published report.

Open published report

Concerns and recipient responses

Select any concern, action or position to view the source wording.

Report evidence summary

Concerns raised5

  1. Lack of appropriate limits on the administration of certain drugs
    Part of recurring concern: Unsafe medication administration
  2. Limited implementation of medication-safety software
  3. Failure to define and document overrides of medication-safety software
    Part of recurring concern: Inadequate safeguards for medication-safety software overrides
Responses linked to these concerns

Each statement is shown once, even when linked to more than one concern.

Actions described in response An action is something a recipient says it has done, is doing, or plans to do in response to a concern raised.8

  1. Action

    Educate staff to use medication libraries and not bypass safety limits except in exceptional circumstances.

    Stated by Oxford University Hospitals NHS Foundation TrustStated plannedThe respondent said that this action was planned when they made their response on 29 November 2021.
  2. Action

    Implement dose-error-reduction infusion pumps and medication libraries across all clinical areas, with specified concentrations and dosing safety limits.

    Stated by Oxford University Hospitals NHS Foundation TrustStated in progressThe respondent said that this action was in progress when they made their response on 29 November 2021.
  3. Action

    Investigate developing limits for entries in the Cerner infusion chart for selected narrow-dose-safety-profile drugs.

    Stated by Oxford University Hospitals NHS Foundation TrustStated in progressThe respondent said that this action was in progress when they made their response on 29 November 2021.

Respondent positions A position is what a recipient says about a concern when it does not describe a specific action.2

  1. Position

    A complete closed-loop drug administration solution cannot be implemented until clinical systems are rationalised into a single system.

    Stated by Oxford University Hospitals NHS Foundation TrustUnable to actThe respondent said that a constraint prevented them from taking the relevant action.

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Lack of appropriate limits on the administration of certain drugs

Wider context from the report

“2. How the system could incorporate appropriate limits on the administration of certain drugs within that system. ”

Is this part of a recurring concern?

Yes — Unsafe medication administration.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Limited implementation of medication-safety software

Wider context from the report

“3. Whether software like Guardrails should be implemented more widely, and consideration given to when and how it is possible to override this, and how that should then be documented. ”

Is this part of a recurring concern?

No recurring-concern membership is currently published.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to define and document overrides of medication-safety software

Wider context from the report

“3. Whether software like Guardrails should be implemented more widely, and consideration given to when and how it is possible to override this, and how that should then be documented. ”

Is this part of a recurring concern?

Yes — Inadequate safeguards for medication-safety software overrides.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Lack of a system for flagging discrepancies between drug prescription and administration

Wider context from the report

“4. Adopting a system of flagging up where prescription and administration of drugs is different. ”

Is this part of a recurring concern?

Yes — Failure to reliably detect discrepancies between prescribed and administered medication.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Lack of a single system for record keeping and monitoring

Wider context from the report

“1. A single system for record keeping and monitoring. ”

Is this part of a recurring concern?

No recurring-concern membership is currently published.

Open source report

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Educate staff to use medication libraries and not bypass safety limits except in exceptional circumstances.

Verbatim wording from the response

“Each medication library will contain a list of medications with specified concentrations and/or dosing safety limits to reduce the risk of infusion related incidents e.g., overdosing or underdosing. Resource will be allocated to ensure that medication entries on the libraries are accurate, relevant, and appropriate so that staff should not need to override safety limits if following usual practice; the software is designed not to be overridden if inappropriate dosing is entered outside of the safe limits put in place.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Implement dose-error-reduction infusion pumps and medication libraries across all clinical areas, with specified concentrations and dosing safety limits.

Verbatim wording from the response

“The Trust is in the process of implementing infusion pumps with inbuilt dose error reduction software (DERS) throughout all clinical areas. Once the project has successfully been completed, clinical areas which use infusion pumps will utilise a medication library to infuse their drugs, if appropriate.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Investigate developing limits for entries in the Cerner infusion chart for selected narrow-dose-safety-profile drugs.

Verbatim wording from the response

“The issue raised refers to the current situation where a user can input a value for a drug infusion rate into the iView infusion section of the Cerner clinical system chart without any limits. This was identified as a contributing factor in the drug dosing error associated with Mr Hussain’s care.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Include automated drug prescription-to-administration specifications in the future single clinical system procurement.

Verbatim wording from the response

“The Trust accepts the need to strengthen the decision support tools within the current clinical systems. We are looking to further improve the embedded system rules regarding drug prescription and administration.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Devise and document an escalation process, standard operating procedure and quick-reference flowsheet for exceptional medication-library overrides.

Verbatim wording from the response

“However, in some exceptional circumstances outside the norm, it may be necessary for patient care to deviate from the specified dosing limits and therefore the infusion pumps offer the capability to infuse medication outside of the library where safety limits are not imposed. Staff will be educated that they must not work outside of the medication library unless in exceptional circumstances and an escalation process will be devised to enable a clear audit trail of all communication and decisions made between staff members which will be documented in the patients’ medical notes. This will be detailed in a standard operating procedure and will contain a flowsheet of the escalation process as a quick reference guide for staff members. A working group has been set up on NICU, who already use a medication library, to trial this.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Introduce new infusion pumps across all sites with bi-directional communication capability between pumps and the Cerner clinical system.

Verbatim wording from the response

“In addition, the Trust is in the process of introducing new infusion pumps across all sites. One of the requirements for the procurement of these pumps was that they should allow bi-directional communication between the pumps and the Cerner clinical system. This would allow auto-programming of the pump from the electronic prescription and would automatically update the hourly infusion rate recorded in the iView infusion section of the drug chart. If the bi-directional communication capability of these pumps were to be used, this would significantly reduce the volume of manually entered data and remove the risk of transcription errors by bedside nurses when programming pumps or recording infusion rates.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 3 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Establish a working group to trial medication-library use on the neurosciences intensive care unit.

Verbatim wording from the response

“However, in some exceptional circumstances outside the norm, it may be necessary for patient care to deviate from the specified dosing limits and therefore the infusion pumps offer the capability to infuse medication outside of the library where safety limits are not imposed. Staff will be educated that they must not work outside of the medication library unless in exceptional circumstances and an escalation process will be devised to enable a clear audit trail of all communication and decisions made between staff members which will be documented in the patients’ medical notes. This will be detailed in a standard operating procedure and will contain a flowsheet of the escalation process as a quick reference guide for staff members. A working group has been set up on NICU, who already use a medication library, to trial this.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Trial medication-library use through the neurosciences intensive care unit working group.

Verbatim wording from the response

“However, in some exceptional circumstances outside the norm, it may be necessary for patient care to deviate from the specified dosing limits and therefore the infusion pumps offer the capability to infuse medication outside of the library where safety limits are not imposed. Staff will be educated that they must not work outside of the medication library unless in exceptional circumstances and an escalation process will be devised to enable a clear audit trail of all communication and decisions made between staff members which will be documented in the patients’ medical notes. This will be detailed in a standard operating procedure and will contain a flowsheet of the escalation process as a quick reference guide for staff members. A working group has been set up on NICU, who already use a medication library, to trial this.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

A complete closed-loop drug administration solution cannot be implemented until clinical systems are rationalised into a single system.

Verbatim wording from the response

“The Trust acknowledges there are multiple clinical systems making up the electronic patient record in the organisation. We accept the need to rationalise the number of clinical systems in use across our critical care units. This is likely to take at least two years to consider and implement.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 1 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Matching prescriptions to constantly adjusted infusion rates is impractical in critical care because bedside rates frequently change.

Verbatim wording from the response

“4. Adopting a system of flagging up where prescription and administration of drugs is different.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 2 · response
Published 29 November 2021

Open published response

Other statements in published responses

These actions and other statements could not be clearly connected to one concern in this report.

Recipient-stated actions An action is something a recipient says it has done, is doing, or plans to do in response to a concern raised.2

  1. 1

    Maintain cross-system transfer mitigations, including drug-chart transcription, intensive-care discharge summaries and automated clinical-note uploads.

    Stated by Oxford University Hospitals NHS Foundation TrustStated completedThe respondent said that this action was complete when they made their response on 29 November 2021.
  2. 2

    Require clinical staff to complete a checklist for safe handovers between intensive care units.

    Stated by Oxford University Hospitals NHS Foundation TrustStated plannedThe respondent said that this action was planned when they made their response on 29 November 2021.

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Maintain cross-system transfer mitigations, including drug-chart transcription, intensive-care discharge summaries and automated clinical-note uploads.

Verbatim wording from the response

“In the intervening period additional mitigations have been taken to address the identified risk and improve patient safety when a patient is moved from one intensive care unit to another.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 1 · response
Published 29 November 2021

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Require clinical staff to complete a checklist for safe handovers between intensive care units.

Verbatim wording from the response

“In the intervening period additional mitigations have been taken to address the identified risk and improve patient safety when a patient is moved from one intensive care unit to another.”

Source location

2021-0399-Response-from-Oxford-University-Hospitals_Published
Page 1 · response
Published 29 November 2021

Open published response
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Information checked against the published report and official responses · Data reviewed 7 Sep 2026 · About data quality and limitations

Official responses located
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Data last updated 7 September 2026