PFD report

Benedict BLYTHE · Prevention of Future Deaths report

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Issued 25 Nov 2025•Cambridgeshire and Peterborough

Report record

Published report and response evidence

This page connects the concerns raised in this report with statements found in recipients’ published responses. A link shows a clear evidence connection; it does not assign responsibility.

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Concerns
8

Raised in this report

Recipients
2

Named on the report

Responses found
2

Of 2 recipients

Stated actions
8

Described in responses

Source document

Full report text

This is the full text from the original published report.

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Concerns and recipient responses

Select any concern, action or position to view the source wording.

Report evidence summary

Concerns raised8

  1. Failure to seize and retain relevant scene samples and evidence for later investigation
    Part of recurring concern: Failure to retain safety-critical source records and evidencePart of recurring concern: Unreliable police investigative evidence gatheringPart of recurring concern: Unreliable sudden-death response and investigation processes
  2. Failure to immediately store or freeze stomach contents for triggering-allergen analysis
    Part of recurring concern: Failure to preserve clinical evidence and data after serious clinical eventsPart of recurring concern: Unreliable retention of biological samples for postmortem investigation
  3. Lack of a standard protocol ensuring appropriate samples are taken at the correct time
    Part of recurring concern: Unreliable coronial autopsy governance and processes
Responses linked to these concerns

Each statement is shown once, even when linked to more than one concern.

Actions described in response An action is something a recipient says it has done, is doing, or plans to do in response to a concern raised.5

  1. Action

    Include revised child-death investigation processes in ongoing training cycles for frontline and investigative staff.

    Stated by Cambridgeshire ConstabularyStated completedThe respondent said that this action was complete when they made their response on 2 December 2025.
  2. Action

    Amend, reissue and widely circulate procedural guidance and aide-memoires for child-death investigations, covering evidence preservation, medical liaison and anaphylaxis considerations.

    Stated by Cambridgeshire ConstabularyStated completedThe respondent said that this action was complete when they made their response on 2 December 2025.
  3. Action

    Establish SOCO liaison and incorporate assessment and seizure of potentially evidential biological samples into child-death forensic strategies.

    Stated by Cambridgeshire ConstabularyStated completedThe respondent said that this action was complete when they made their response on 2 December 2025.

Respondent positions A position is what a recipient says about a concern when it does not describe a specific action.4

  1. Position

    Suspected anaphylaxis should be raised with the Coroner’s officer by the referring medical practitioner or police before the pathologist is contacted.

    Stated by Royal College of PathologistsRedirects responsibilityThe respondent said that another organisation was responsible for deciding or taking action.

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to seize and retain relevant scene samples and evidence for later investigation

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to retain safety-critical source records and evidence; Unreliable police investigative evidence gathering; Unreliable sudden-death response and investigation processes.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to immediately store or freeze stomach contents for triggering-allergen analysis

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to preserve clinical evidence and data after serious clinical events; Unreliable retention of biological samples for postmortem investigation.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Lack of a standard protocol ensuring appropriate samples are taken at the correct time

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Unreliable coronial autopsy governance and processes.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to collect and store an early post-mortem blood sample for later analysis

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Unreliable coronial autopsy governance and processes; Unreliable retention of biological samples for postmortem investigation.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to retain hospital blood samples for testing

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to retain safety-critical source records and evidence; Unreliable retention of biological samples for postmortem investigation.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to raise possible anaphylaxis deaths with the senior coroner at the earliest opportunity

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to reliably report deaths to coroners.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to collect blood samples for mast cell tryptase and specific IgE serology in suspected anaphylaxis

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to recognise and respond to anaphylaxis.

Open source report

Source evidence

How this individual concern was interpreted

PFD Monitor created a concise, searchable interpretation from the report wording shown below. Response links show a clear evidence connection; they do not assign responsibility.

PFD Monitor interpretation

Failure to collect and retain tissue samples in suspected anaphylaxis

Wider context from the report

“1) In relation to Pathology That Kennedy samples collected during a post-mortem examination, should be revised to include the following in cases of suspected anaphylaxis: a. blood samples for mast cell tryptase and sp IgE serology 2 suspected allergens b. stomach contents to be immediately stored (and/or frozen) by the pathologist for the analysis of the presence of the triggering allergen c. blood samples if taken at hospital should not be destroyed but retained for testing d. that an early blood sample is taken after death and stored for later analysis e. that the possibility that the death is due to anaphylaxis is raised with the senior coroner for the area where the death occurred at the earliest opportunity f. tissue samples are taken and retained. g. Consideration given to the development of a standard protocol to ensure appropriate samples are taken at the correct time to assist later investigation. 2.) The police investigation: In the circumstances where there is an unexplained death of a child or the person and where that data samples and evidence available at the scene including by way of example vomitus, that the police should include as part of their investigation, the seizure and retention of any such material for the purposes of later investigation either by the Police Pathologist or the Coroner. ”

Is this part of a recurring concern?

Yes — Failure to retain safety-critical source records and evidence; Unreliable retention of biological samples for postmortem investigation.

Open source report

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Include revised child-death investigation processes in ongoing training cycles for frontline and investigative staff.

Verbatim wording from the response

“Finally, the revised processes are now included within ongoing training cycles for child death investigations, meaning all staff involved in frontline or investigative roles will receive regular reinforcement of expectations and good practice standards. This training emphasises the forensic, investigative, and safeguarding considerations required in early decision-making, helping ensure that opportunities to understand cause of death are preserved and that future investigations are informed by best practice.”

Source location

Response form Cambridgeshire Constabulary
Page 2 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Amend, reissue and widely circulate procedural guidance and aide-memoires for child-death investigations, covering evidence preservation, medical liaison and anaphylaxis considerations.

Verbatim wording from the response

“Second, the Constabulary has amended and re-issued internal procedural guidance and aide-memoire materials relating to child death investigations. These documents have been circulated widely to all officers and staff who may attend such incidents,”

Source location

Response form Cambridgeshire Constabulary
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Establish SOCO liaison and incorporate assessment and seizure of potentially evidential biological samples into child-death forensic strategies.

Verbatim wording from the response

“First, full liaison with Scenes of Crime Officers (SOCOs) has been established to ensure that, in all cases of unexplained child death, the potential evidential value of samples found at the scene—such as vomitus or other biological material—is actively recognised and considered. SOCOs have been formally briefed, and the need to assess and seize such samples is now incorporated into the forensic strategy in consultation with the Senior Investigating Officer. This ensures that opportunities to preserve material for the Coroner, the Pathologist, or investigators are not missed.”

Source location

Response form Cambridgeshire Constabulary
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Publish autopsy guidelines for suspected acute anaphylaxis, including blood and stomach-content sampling guidance.

Verbatim wording from the response

“The Kennedy Protocol has not been formally updated since 2016; it is not known when or if the protocol is to be revised. Since then Autopsy guidelines have been published on sudden unexpected death in infancy and childhood in 2023 under the remit of the Death Investigation Committee at the Royal College of Pathologists and these have superseded the 2016 publication. Neither the 2016 or 2023 guidelines included samples in cases of suspected anaphylaxis. However, the RCPath published autopsy guidelines on autopsies for suspected acute anaphylaxis (includes anaphylactic shock and anaphylactic asthma) in 2018. This document does include very specific guidance of sampling blood and stomach contents in such cases together with caveats for interpreting mast cell tryptase levels.”

Source location

Response from Royal College of Pathologists
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Query the relevant guideline authors about adding IgE testing to an updated autopsy guideline.

Verbatim wording from the response

“There are guidelines published by the RCPath for anaphylaxis (referenced below) of note; IgE is not specifically referenced in any of the documents and this will be queried with the authors of the relevant guideline to be included in an updated version. The reference below was published after the guideline was written.”

Source location

Response from Royal College of Pathologists
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Suspected anaphylaxis should be raised with the Coroner’s officer by the referring medical practitioner or police before the pathologist is contacted.

Verbatim wording from the response

“If a death due to anaphylaxis is suspected, this should be raised by the initial referring medical practitioner to the Coroner’s officer or by the police. The case to which the Coroner’s queries are raised should have anaphylaxis or allergic reaction in the potential cause of death or in the deceased’ situational history before the pathologist was contacted. It is usual practice for the autopsy pathologist to communicate a suspected cause of death to the Coroner after the initial examination pending the results of further investigations, however, it is not always possible for a pathologist to be definite at that stage.”

Source location

Response from Royal College of Pathologists
Page 2 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Published anaphylaxis autopsy guidance and expected use of relevant guidance are considered sufficient despite paediatric guidelines lacking specific anaphylaxis details.

Verbatim wording from the response

“The Kennedy Protocol has not been formally updated since 2016; it is not known when or if the protocol is to be revised. Since then Autopsy guidelines have been published on sudden unexpected death in infancy and childhood in 2023 under the remit of the Death Investigation Committee at the Royal College of Pathologists and these have superseded the 2016 publication. Neither the 2016 or 2023 guidelines included samples in cases of suspected anaphylaxis. However, the RCPath published autopsy guidelines on autopsies for suspected acute anaphylaxis (includes anaphylactic shock and anaphylactic asthma) in 2018. This document does include very specific guidance of sampling blood and stomach contents in such cases together with caveats for interpreting mast cell tryptase levels.”

Source location

Response from Royal College of Pathologists
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Femoral blood sampling in very young children may be impractical, requiring alternative sites that complicate interpretation of mast cell tryptase levels.

Verbatim wording from the response

“Early blood sampling is indicated but timing may be determined by the local post-mortem HTA 2004 arrangements in individual hospitals. In addition, it is extremely difficult to obtain femoral vessel blood samples in very young children purely due to the size of the individual and blood may”

Source location

Response from Royal College of Pathologists
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent position was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Sample retention is determined by the requesting Coroner and subsequently by parental or next-of-kin consent under the Human Tissue Act 2004.

Verbatim wording from the response

“In all Coronial post-mortem examinations in children, tissue samples are taken primarily in accordance with the published protocols and also any that are relevant to ascertaining the cause of death. Retention of samples is determined initially by the Coroner requesting the post-mortem examination and thereafter by parental / next-of-kin consent in line with the Human Tissue Act 2004.”

Source location

Response from Royal College of Pathologists
Page 2 · response
Published 2 December 2025

Open published response

Other statements in published responses

These actions and other statements could not be clearly connected to one concern in this report.

Recipient-stated actions An action is something a recipient says it has done, is doing, or plans to do in response to a concern raised.3

  1. 1

    Incorporate updated child-death investigation guidance into the SaferTogether departmental newsletter for specialist investigators.

    Stated by Cambridgeshire ConstabularyStated completedThe respondent said that this action was complete when they made their response on 2 December 2025.
  2. 2

    Publish autopsy guidelines on sudden unexpected death in infancy and childhood.

    Stated by Royal College of PathologistsStated completedThe respondent said that this action was complete when they made their response on 2 December 2025.
  3. 3

    Raise adding a cross-reference to relevant autopsy guidance with the paediatric autopsy guideline authors.

    Stated by Royal College of PathologistsStated plannedThe respondent said that this action was planned when they made their response on 2 December 2025.

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Incorporate updated child-death investigation guidance into the SaferTogether departmental newsletter for specialist investigators.

Verbatim wording from the response

“Third, the updated guidance has been incorporated into the Protecting Vulnerable People (PVP) departmental newsletter, ‘SaferTogether’, ensuring that specialist investigators—who manage the majority of child death responses—are fully aware of the changes. Embedding these updates within existing communication channels supports strong organisational understanding and consistent practice across teams.”

Source location

Response form Cambridgeshire Constabulary
Page 2 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Publish autopsy guidelines on sudden unexpected death in infancy and childhood.

Verbatim wording from the response

“The Kennedy Protocol has not been formally updated since 2016; it is not known when or if the protocol is to be revised. Since then Autopsy guidelines have been published on sudden unexpected death in infancy and childhood in 2023 under the remit of the Death Investigation Committee at the Royal College of Pathologists and these have superseded the 2016 publication. Neither the 2016 or 2023 guidelines included samples in cases of suspected anaphylaxis. However, the RCPath published autopsy guidelines on autopsies for suspected acute anaphylaxis (includes anaphylactic shock and anaphylactic asthma) in 2018. This document does include very specific guidance of sampling blood and stomach contents in such cases together with caveats for interpreting mast cell tryptase levels.”

Source location

Response from Royal College of Pathologists
Page 1 · response
Published 2 December 2025

Open published response

Source evidence

How this respondent action was interpreted

PFD Monitor created a concise, searchable interpretation from the published response wording shown below.

PFD Monitor interpretation

Raise adding a cross-reference to relevant autopsy guidance with the paediatric autopsy guideline authors.

Verbatim wording from the response

“In summary: Post-mortem guidelines are in place for allergic / anaphylactic deaths. IgE is not currently in the protocol and this will be raised with the author group of the relevant autopsy guideline. Likewise, including a cross-reference to other autopsy guidelines will be raised with the author group of the paediatric autopsy guidelines.”

Source location

Response from Royal College of Pathologists
Page 2 · response
Published 2 December 2025

Open published response
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Information checked against the published report and official responses · Data reviewed 7 Sep 2026 · About data quality and limitations

Official responses located
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Data last updated 7 September 2026